The Sarcomas

  • Aaron M. Bruce
  • James M. Spencer


  • EPIDEMIOLOGY: Collectively uncommon with exception of AFX, seen principally in elderly, equal gender.

  • PATHOGENESIS: AFX and AS–UV light, DFSP-translocation of PDGF and collagen genes t(17;22).

  • PATHOLOGY: AFX-storiform, anaplasia; DFSP-storiform, no anaplasia; LS-fascicles; AS-anastomosing sinusoids.

  • CLINICAL: AFX-face, ulcerated papule; DFSP-nodule trunk and exts.; LS-nodules; AS- face violaceous patch.


Spindle Cell Collagen Gene Malignant Fibrous Histiocytoma Fibrous Histiocytoma Deep Soft Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Aaron M. Bruce
    • 1
  • James M. Spencer
    • 2
    • 3
  1. 1.Department of Dermatology, Suncoast HospitalNova Southeastern UniversityLargoUSA
  2. 2.Clinical Dermatology, Mount Sinai School of MedicineNew YorkUSA
  3. 3.Spencer Dermatology and Surgery CenterSt. PetersburgUSA

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