Paget’s Disease

  • Michael B. Morgan


  • EPIDEMIOLOGY: Uncommon, elderly, mammary and extra-mammary.

  • ETIOLOGY: Unknown

  • PATHOLOGY: Single and nested clear cells throughout the epithelium, CEA+, CK-7+, EMA+.

  • CLINICAL: Scaly or erythematous patch areola or genitalia.

  • TREATMENT: Supportive for mammary, excision with genitourinary/gastrointestinal w/u for extra-mammary.


Squamous Cell Carcinoma Cell Leukocyte Common Antigen Mohs Micrographic Surgery Erythematous Patch Visceral Malignancy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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    Jones R, Austin C, Ackerman A. Extramammary pagets disease: a critical reexamination. Am J Dermatopathol. 1979;1:101.CrossRefPubMedGoogle Scholar
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    Lee S, Roth L, Ehrlich C, et al. Extramammary pagets disease of the vulva. A clinicopathologic study of 13 cases. Cancer. 1977;39:2540.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Michael B. Morgan
    • 1
  1. 1.Bay Area Dermatopathology Ameripath, and Director of Primary Care Institute, Dermpath DiagnosticsUniversity of South Florida College of Medicine, and Director, Dermatopathology, Haley V.A. Hospital, and Managing DirectorTampaUSA

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