Sebaceous Tumors

  • Michael B. Morgan


  • EPIDEMIOLOGY : Uncommon, approximately 1/2 occur on eyelids, elderly with equal gender, syndromic females are at a younger age.

  • PATHOGENESIS : Derive from Meibomian glands, other sebaceous glands, assoc. with XRT and Muir-Torre Syndrome.

  • PATHOLOGY: Pagetoid or invasive basaloid or squamous cells with sebocytic cells showing clear cytoplasmic vacuoles.

  • CLINICAL : Non-descript ulcerating papule, may be yellow in appearance or involve both eyelids.

  • PROGNOSIS : Poor with 25% patients with metastatic disease at diagnosis with 50% 5-year mortality, lymph nodes.


Basal Cell Carcinoma Sebaceous Gland Cytoplasmic Vacuole Meibomian Gland Sebaceous Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Nelson B, Hamlet K, Hillard M, et al. Sebaceous carcinoma. JAAD. 1995; 33: 1.Google Scholar
  2. 2.
    Rao N, Hidayat A, McClean I, et al. sebaceous carcinoma of the ocular adnexae: a clinicopathalogic study of 104 cases, with 5 year follow up. Hum Pathol. 1982; 13: 113.CrossRefPubMedGoogle Scholar
  3. 3.
    Schwartz R, Torre D. The Muir-Torre syndrome: a 25-year retrospect. JAAD. 1995;33: 90.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Michael B. Morgan
    • 1
  1. 1.Bay Area Dermatopathology Ameripath, and Director of Primary Care Institute, Dermpath DiagnosticsUniversity of South Florida College of Medicine, and Director, Dermatopathology, Haley V.A. Hospital, and Managing DirectorTampaUSA

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