Merkel Cell Carcinoma

  • Michael B. Morgan


  • EPIDEMIOLOGY : Uncommon, elderly with equal gender distribution.

  • ETIOLOGY : Ultraviolet light, immunosupression, polyoma virus.

  • PATHOLOGY: Diffuse, trabecular, or nodular aggregates of small blue cells with scant cytoplasm.

  • PROGNOSIS : Poor, 5-year 50% mortality adverse outcome with lymph node or systemic spread.


Basal Cell Carcinoma Merkel Cell Carcinoma Thyroid Transcription Factor Permanent Section Equal Gender Distribution 
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  1. 1.
    Boyer J, Zitelli J, Brodland D, et al. Local control of primary Merkel cell carcinoma: review of 45 cases treated with Mohs micrographic surgery with and without adjuvant radiation. JAAD. 2002; 47: 885.Google Scholar
  2. 2.
    Morgan MB. Merkel cell carcinoma. In: Morgan MB, ed. Deadly Dermatologic Diseases. New York: Springer; 2007.Google Scholar
  3. 3.
    O’Connor W. Merkel cell carcinoma. Comparison of Mohs micrographic surgery and wide excision. In eighty-six patients. Dermatol Surg. 1997; 23: 929.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Michael B. Morgan
    • 1
  1. 1.Bay Area Dermatopathology Ameripath, and Director of Primary Care Institute, Dermpath DiagnosticsUniversity of South Florida College of Medicine, and Director, Dermatopathology, Haley V.A. Hospital, and Managing DirectorTampaUSA

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