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Mohs and Frozen Section Overview

  • Michael B. Morgan
  • Terri Bowland
Chapter

Abstract

The evaluation of frozen section prepared tissues derived from the skin constitutes a burgeoning area of hospital- and outpatient-based pathology practice. Frozen section cutaneous pathology encompasses a diverse array of techniques for preparing the skin specimen and incorporates a variety of diagnostic methodologies. This book will principally address the histologic interpretation of the various cutaneous neoplasms encountered with the Mohs micrographic frozen method and traditional fresh-frozen pathology. Unusual diagnostic applications of frozen sections such as frozen section immunopathology, special techniques including the adjudication of the scalded skin syndrome with toxic epidermal necrolysis and unconventional topics such as perineural pathology and quality assurance with technique trouble-shooting will also be covered. Frozen section intra-operative consultation traditionally involves the evaluation of neoplastic tissues for diagnosis confirmation, application of special techniques and/or the evaluation of tissue margins.

Keywords

Freeze Section Surgical Margin Basal Cell Carcinoma Toxic Epidermal Necrolysis Merkel Cell Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Michael B. Morgan
    • 1
  • Terri Bowland
    • 2
  1. 1.Bay Area Dermatopathology Ameripath, and Director of Primary Care Institute, Dermpath DiagnosticsUniversity of South Florida College of Medicine, and Director, Dermatopathology, Haley V.A. Hospital, and Managing DirectorTampaUSA
  2. 2.Group Practice, Dermatology, ReadingReadingUSA

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