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Control of Bleeding in Cancer

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Coagulation in Cancer

Part of the book series: Cancer Treatment and Research ((CTAR,volume 148))

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Clinically significant bleeding occurs in approximately 10% of the patients with advanced cancer [1]. Massive bleeding from the nose, pharynx, lung, or gastrointestinal tract constitutes a major challenge; however, it is difficult to predict who will have a serious bleeding event requiring special management and interventions. Bleeding in patients with cancer may present as a localized bleeding diathesis, more often as a result of local injury by tumor invasion or as a generalized hemorrhagic diathesis caused by thrombocytopenia, platelet dysfunction, coagulation factor deficiencies, presence of inhibitors or increased fibrinolysis. Mild persistent bleeding can be distressing for the patient, family members and caregivers; however, catastrophic massive bleeding may also occur, demanding urgent therapeutic intervention.

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  1. Department of Hematology-Oncology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile

    Jaime Pereira

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    Pereira, J. (2009). Control of Bleeding in Cancer. In: Kwaan, H., Green, D. (eds) Coagulation in Cancer. Cancer Treatment and Research, vol 148. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-79962-9_18

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