Procedures in Critical Care: Dialysis and Apheresis



Acute renal injury in the intensive care unit (ICU) is associated with significant excess mortality. A rise in the serum creatinine of 0.3 mg/dl is associated with worse outcomes in critically ill patients.1,2 Using the consensus definition of acute renal injury, the so-called RIFLE criteria 3, 4 (Fig. 8-1), the odds ratio for death increases from approximately 2.5 in those patients classified as having renal Risk to 5 for renal Injury and finally to 10 for those with Failure.5 Even after adjusting for other comorbidities, renal injury in the ICU is an independent risk factor for death 6 – 8 and the need for acute dialytic therapy in the ICU is associated with 50–60% mortality. 9, 10


Peritoneal Dialysis Renal Replacement Therapy Continuous Renal Replacement Therapy Blood Flow Rate Replacement Fluid 
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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Hypertension and Transplant Medicine, Section of NephrologyMedical College of GeorgiaAugustaUSA

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