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Astrocytes in Control of the Biophysical Properties of Extracellular Space

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Astrocytes in (Patho)Physiology of the Nervous System

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Abbreviations

α:

Extracellular volume fraction

ADC:

Apparent diffusion coefficient

ADCw:

Apparent diffusion coefficient of water

AMPA:

α-Amino-3-hydroxy-5-metyl-isoxazol-4-propionic acid

CNS:

Central nervous system

CSPG:

Chondroitin-sulphate proteoglycan

D:

Diffusion coefficient

dpw:

Day post wounding

DW-MRI:

Diffusion-weighted magnetic resonance imaging

EAE:

Experimental autoimmune encephalomyelitis

ECM:

Extracellular matrix

ECS:

Extracellular space

GABA:

γ-Aminobutyric acid

GFAP:

Glial fibrillary acidic protein

IOS:

Intrinsic optical signals

ISM:

Ion-selective microelectrode

k':

Nonspecific cellular uptake

[K+]e:

Extracellular concentration of potassium ions

λ :

Tortuosity

NMDA:

N-methyl-d-aspartate

pHe:

Extracellular pH

pHi:

Intracellular pH

RVD:

Regulatory volume decrease

TEA:

Tetraethylammonium

TMA:

Tetramethylammonium

TN:

Tenascin

WHO:

World Health Organization

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Acknowledgments

The authors acknowledge the support of grants AV0Z50390512 from the Academy of Sciences of the Czech Republic and LC554 from the Ministry of Education, Youth and Sports of the Czech Republic.

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    1. Lydia Vargova
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    2. Eva Sykova
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      Vargova, L., Sykova, E. (2009). Astrocytes in Control of the Biophysical Properties of Extracellular Space. In: Haydon, P., Parpura, V. (eds) Astrocytes in (Patho)Physiology of the Nervous System. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-79492-1_9

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