Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Altman, J.D., Moss, P.A., Goulder, P.J., Barouch, D.H., McHeyzer-Williams, M.G., Bell, J.I., McMichael, A.J., Davis, M.M. (1996). Phenotypic analysis of antigen-specific T lymphocytes. Science 274, 94–96
Badovinac, V.P., Haring, J.S., Harty, J.T. (2007). Initial T cell receptor transgenic cell precursor frequency dictates critical aspects of the CD8(+) T cell response to infection. Immunity 26, 827–841
Badovinac, V.P., Harty, J.T. (2006). Programming, demarcating, and manipulating CD8+ T-cell memory. Immunological Reviews 211, 67–80
Baron, V., Bouneaud, C., Cumano, A., Lim, A., Arstila, T.P., Kourilsky, P., Ferradini, L., Pannetier, C. (2003). The repertoires of circulating human CD8(+) central and effector memory T cell subsets are largely distinct. Immunity 18, 193–204
Blattman, J.N., Antia, R., Sourdive, D.J., Wang, X., Kaech, S.M., Murali-Krishna, K., Altman, J.D., Ahmed, R. (2002). Estimating the precursor frequency of naive antigen-specific CD8 T cells. Journal of Experimental Medicine 195, 657–664
Bousso, P., Casrouge, A., Altman, J.D., Haury, M., Kanellopoulos, J., Abastado, J.P., Kourilsky, P. (1998). Individual variations in the murine T cell response to a specific peptide reflect variability in naive repertoires. Immunity 9, 169–178
Bousso, P., Robey, E. (2003). Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes. Nature Immunology 4, 579–585
Butz, E.A., Bevan, M.J. (1998). Massive expansion of antigen-specific CD8+ T cells during an acute virus infection. Immunity 8, 167–175
Casrouge, A., Beaudoing, E., Dalle, S., Pannetier, C., Kanellopoulos, J., Kourilsky, P. (2000). Size estimate of the alpha beta TCR repertoire of naive mouse splenocytes. Journal of Immunology 164, 5782–5787
Ford, M.L., Koehn, B.H., Wagener, M.E., Jiang, W., Gangappa, S., Pearson, T.C., Larsen, C.P. (2007). Antigen-specific precursor frequency impacts T cell proliferation, differentiation, and requirement for costimulation. Journal of Experimental Medicine 204, 299–309
Foulds, K.E., Shen, H. (2006). Clonal competition inhibits the proliferation and differentiation of adoptively transferred TCR transgenic CD4 T cells in response to infection. Journal of Immunology 176, 3037–3043
Foulds, K.E., Zenewicz, L.A., Shedlock, D.J., Jiang, J., Troy, A.E., Shen, H. (2002). Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses. Journal of Immunology 168, 1528–1532
Hataye, J., Moon, J.J., Khoruts, A., Reilly, C., Jenkins, M.K. (2006). Naive and memory CD4+ T cell survival controlled by clonal abundance. Science 312, 114–116
Heath, W.R., Belz, G.T., Behrens, G.M., Smith, C.M., Forehan, S.P., Parish, I.A., Davey, G.M., Wilson, N.S., Carbone, F.R., Villadangos, J.A. (2004). Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunological Reviews 199, 9–26
Huster, K.M., Busch, V., Schiemann, M., Linkemann, K., Kerksiek, K.M., Wagner, H., Busch, D.H. (2004). Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets. Proceedings of the National Academy of Sciences of the United States of America 101, 5610–5615
Kaech, S.M., Ahmed, R. (2001). Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nature Immunology 2, 415–422
Kaech, S.M., Tan, J.T., Wherry, E.J., Konieczny, B.T., Surh, C.D., Ahmed, R. (2003). Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nature Immunology 4, 1191–1198
Kearney, E.R., Pape, K.A., Loh, D.Y., Jenkins, M.K. (1994). Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1, 327–339
Kedzierska, K., Day, E.B., Pi, J., Heard, S.B., Doherty, P.C., Turner, S.J., Perlman, S. (2006). Quantification of repertoire diversity of influenza-specific epitopes with predominant public or private TCR usage. Journal of Immunology 177, 6705–6712
Kemp, R.A., Powell, T.J., Dwyer, D.W., Dutton, R.W. (2004). Cutting edge: regulation of CD8+ T cell effector population size. Journal of Immunology 173, 2923–2927
Lanzavecchia, A., Sallusto, F. (2000). Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells. Science 290, 92–97
Marzo, A.L., Klonowski, K.D., Le Bon, A., Borrow, P., Tough, D.F., Lefrancois, L. (2005). Initial T cell frequency dictates memory CD8+ T cell lineage commitment. Nature Immunology 6, 793–799
Masopust, D., Vezys, V., Marzo, A.L., Lefrancois, L. (2001). Preferential localization of effector memory cells in nonlymphoid tissue. Science 291, 2413–2417
Mempel, T.R., Henrickson, S.E., Andrian, U.H. Von (2004). T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427, 154–159
Moon, J.J., Chu, H.H., Pepper, M., McSorley, S.J., Jameson, S.C., Kedl, R.M., Jenkins, M.K. (2007). Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude. Immunity 27, 203–213
Pewe, L.L., Netland, J.M., Heard, S.B., Perlman, S. (2004). Very diverse CD8 T cell clonotypic responses after virus infections. Journal of Immunology 172, 3151–3156
Reiner, S.L., Sallusto, F., Lanzavecchia, A. (2007). Division of labor with a workforce of one: challenges in specifying effector and memory T cell fate. Science 317, 622–625
Sallusto, F., Lenig, D., Forster, R., Lipp, M., Lanzavecchia, A. (1999). Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401, 708–712
Stoll, S., Delon, J., Brotz, T.M., Germain, R.N. (2002). Dynamic imaging of T cell–dendritic cell interactions in lymph nodes. Science 296, 1873–1876
Wherry, E.J., Teichgraber, V., Becker, T.C., Masopust, D., Kaech, S.M., Antia, R., Andrian, U.H., von Ahmed, R. (2003). Lineage relationship and protective immunity of memory CD8 T cell subsets. Nature Immunology 4, 225–234
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2009 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Wirth, T., Harty, J.T. (2009). Initial TCR transgenic precursor frequency alters functional behaviour of CD8 T cells responding to acute infection. In: Schoenberger, S., Katsikis, P., Pulendran, B. (eds) Crossroads between Innate and Adaptive Immunity II. Advances in Experimental Medicine and Biology, vol 633. Springer, New York, NY. https://doi.org/10.1007/978-0-387-79311-5_7
Download citation
DOI: https://doi.org/10.1007/978-0-387-79311-5_7
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-79310-8
Online ISBN: 978-0-387-79311-5
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)