Neuronal Noise pp 185-241 | Cite as

Recreating Synaptic Noise Using Dynamic-Clamp

Part of the Springer Series in Computational Neuroscience book series (NEUROSCI, volume 8)


This chapter will cover one of the most promising and elegant approach for studying the effect of synaptic noise on neurons: the dynamic-clamp injection of artificial conductance-based synaptic noise.We start by an introduction to the dynamic-clamp technique, and we next describe the “re-creation” of in vivo-like activity states in neurons maintained in vitro. We then overview the consequences of synaptic noise on the integrative properties of neurons, as found by dynamic-clamp experiments.


Integrative Property Thalamic Neuron Synaptic Conductance Spike Threshold Burst Response 
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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Unité de Neuroscience, Information et ComplexitéCNRS, UPR-2191Gif-sur-YvetteFrance

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