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Cardiovascular Disease and Inflammation

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Book cover Nolph and Gokal's Textbook of Peritoneal Dialysis

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Patients with chronic kidney disease (CKD) have a markedly reduced lifespan. Cardiovascular disease (CVD), including stroke, acute myocardial infarction (AMI), sudden death, peripheral vascular disease (PVD), and congestive heart failure (CHF), accounts for premature death in more than 50% of dialysis patients from North America and Europe [1]. As premature CVD accounts for the majority of all-cause mortality, CKD should, like diabetes mellitus (DM), be considered a “high risk” group for CVD [2] and vascular disease should be treated with the same maximum armatorium of drugs and with active interventions, such as coronary artery by-pass graft (CABG), as would be indicated in the high-risk segments of the nonrenal population. This includes the use of antiplatelet agents, angiotensin-converting-enzyme-inhibitors (ACE-I), angiotensin receptor blockers (ARBs), β-blockers, nitroglycerine, and statins.

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Authors and Affiliations

  1. Division of Renal Medicine K56, Karolinska University Hospital at Huddinge, 141 86, Stockholm, Sweden

    P. Stenvinkel

  2. Department of Internal Medicine, Division of Nephrology, Im Neuenheimer Feld 162, University of Heidelberg, Heidelberg, Germany

    E. Ritz

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Correspondence to P. Stenvinkel .

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  1. School of Medicine Department of Medicine Division of Nephrology, MA436 Health Sciences Center, Columbia, MO 65212, USA

    Ramesh Khanna

  2. Academic Medical Center Dept. Medicine, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands

    Raymond T. Krediet

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Stenvinkel, P., Ritz, E. (2009). Cardiovascular Disease and Inflammation. In: Khanna, R., Krediet, R.T. (eds) Nolph and Gokal's Textbook of Peritoneal Dialysis. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-78940-8_23

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