Two-Component Signaling Systems and Cell Cycle Control in Caulobacter crescentus

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 631)


Recent work on the regulation of prokaryotic growth and development by two-component systems (TCS) has revealed unsuspected levels of complexity. In the dimorphic freshwater bacterium Caulobacter crescentus, TCS provide stringent temporal and spatial control of cellular development and cell-cycle progression. While the environmental signals modulating TCS regulatory networks are largely unknown, the components of the network and their interactions with each other are increasingly well-defined. Here, we present an overview of TCS regulation of cell-cycle control in C. crescentus.


Response Regulator Histidine Kinase Chromosome Replication Swarmer Cell Caulobacter Crescentus 


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Copyright information

© Landes Bioscience and Springer Science+Business Media 2008

Authors and Affiliations

  • Erin B. Purcell
    • 2
  • Cara C. Boutte
    • 2
  • Sean Crosson
    • 2
    • 1
  1. 1.Committee on MicrobiologyThe University of Chicago, Gordon Center for Integrative ScienceChicagoUSA
  2. 2.Department of Biochemistry and Molecular BiologyThe University of Chicago, Gordon Center for Integrative ScienceChicagoUSA

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