Introduction to Bacterial Signal Transduction Networks

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 631)


Transcriptional analysis using a DNA microarray is an extremely efficient method for analyzing two-component signal transduction networks. Here we introduce three such networks in Escherichia coli that were clarified using a DNA microarray: a PhoQ/PhoP system that senses extracellular Mg2+ and controls the gene expression for adaptation to environmental Mg2+ deprivation (Mg2+ stimulon); an, EvgS/EvgA signal transduction system that activates expression of multiple drug efflux pumps and acid resistance genes; and a signal transduction cascade between EvgS/EvgA and PhoQ/PhoP.


Histidine Kinase Signal Transduction Cascade Signal Transduction Network Cognate Response Regulator Phosphorelay System 
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Copyright information

© Landes Bioscience and Springer Science+Business Media 2008

Authors and Affiliations

  1. 1.Department of Bioscience, Graduate School of AgricultureKinki UniversityNaraJapan

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