Abstract
Transcriptional analysis using a DNA microarray is an extremely efficient method for analyzing two-component signal transduction networks. Here we introduce three such networks in Escherichia coli that were clarified using a DNA microarray: a PhoQ/PhoP system that senses extracellular Mg2+ and controls the gene expression for adaptation to environmental Mg2+ deprivation (Mg2+ stimulon); an, EvgS/EvgA signal transduction system that activates expression of multiple drug efflux pumps and acid resistance genes; and a signal transduction cascade between EvgS/EvgA and PhoQ/PhoP.
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© 2008 Landes Bioscience and Springer Science+Business Media
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Eguchi, Y., Utsumi, R. (2008). Introduction to Bacterial Signal Transduction Networks. In: Utsumi, R. (eds) Bacterial Signal Transduction: Networks and Drug Targets. Advances in Experimental Medicine and Biology, vol 631. Springer, New York, NY. https://doi.org/10.1007/978-0-387-78885-2_1
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DOI: https://doi.org/10.1007/978-0-387-78885-2_1
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-78884-5
Online ISBN: 978-0-387-78885-2
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