The Role of Hematopoietic Stem Cell Transplantation in Hodgkin Lymphoma

  • Craig Moskowitz
  • John Sweetenham
Part of the Cancer Treatment and Research book series (CTAR, volume 144)


Autologous hematopoietic stem cell transplantation (HSCT) has been a standard component of therapy for most patients with relapsed and refractory Hodgkin’s lymphoma (HL; a.k.a. Hodgkin’s disease) for many years. The emergence of new first-line therapies for HL, the application of new staging and imaging techniques and the introduction of nonmyeloablative conditioning for allogeneic HSCT have resulted in a re-evaluation of the role of stem cell transplant strategies in this disease. As first-line therapy continues to improve, the number of patients requiring salvage therapy with HSCT is likely to fall. However, it is likely that this patient population will be particularly challenging, requiring novel salvage approaches.

Autologous HSCT in Hodgkin Lymphoma

Relapsed Disease

The use of conventional-dose salvage therapy for patients with HL who relapse after initial chemotherapy has been disappointing. Studies in patients relapsing after MOPP (mechlorethamine, vincristine,...


Overall Survival Hematopoietic Stem Cell Transplantation Allogeneic Hematopoietic Stem Cell Transplantation Autologous Hematopoietic Stem Cell Transplantation Nonmyeloablative Conditioning 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Memorial Sloan-Kettering Cancer CenterNew YorkUSA

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