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The Epidemiology of Transplant-Associated Keratinocyte Cancers in Different Geographical Regions

  • Charlotte M. Proby
  • Hermina C. Wisgerhof
  • Delphine Casabonne
  • Adele C. Green
  • Catherine A. Harwood
  • Jan N. Bouwes Bavinck
Part of the Cancer Treatment and Research book series (CTAR, volume 146)

There are believed to be more than 1 million individuals worldwide currently with an organ allograft [1], and a further steep increase in numbers is expected in the next decade. The life-enhancing benefits of organ transplantation are undisputed, but come at a cost. Complications from graft-preserving iatrogenic immunosuppression include a significantly increased risk of malignancy. More than 40 primary malignant neoplasms were reported in the first 4,000 patients to undergo renal transplantation [2], and this early observation has been consistently supported by subsequent studies [3–7].

Keywords

Transplant Recipient Skin Cancer Basal Cell Carcinoma Renal Transplant Recipient Standardize Incidence Ratio 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Charlotte M. Proby
    • 1
  • Hermina C. Wisgerhof
    • 2
  • Delphine Casabonne
    • 3
  • Adele C. Green
    • 4
  • Catherine A. Harwood
    • 5
    • 6
  • Jan N. Bouwes Bavinck
    • 7
  1. 1.Division of Surgery and OncologyCollege of Medicine, Dentistry and Nursing, University of Dundee, Ninewells HospitalDundeeUnited Kingdom
  2. 2.Department of DermatologyLeiden University Medical CenterThe Netherlands
  3. 3.Cancer Epidemiology Unit, Richard Doll BuildingUniversity of OxfordOxfordUnited Kingdom
  4. 4.Queensland Institute of Medical ResearchBrisbaneAustralia
  5. 5.Center for Cutaneous Research, Institute of Cell andMolecular ScienceBarts and The London, School of Medicine and Dentistry, Queen Mary University of LondonLondon
  6. 6.Department of DermatologyBarts and the London NHS TrustLondonUnited Kingdom
  7. 7.Department of DermatologyLeiden University Medical CenterThe Netherlands

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