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Skin Immune System

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Skin Cancer after Organ Transplantation

Part of the book series: Cancer Treatment and Research ((CTAR,volume 146))

The skin is, in weight, the largest organ of the human body. Its primary role is that of a physical and biological barrier. This principal function is most apparent in the skin’s relative lack of permeability for agents from outside, including microbes and parasites, but also for water and water-soluble compounds. The resistance to exogenous influences is mainly the result of the physicochemical properties of its outermost layer, the corneal layer of the epidermis (stratum corneum). In addition to its function as a barrier against potentially harmful outside effects, the skin also serves to maintain the homeostasis of the “milieu intùrieure” by preventing desiccation.

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Authors and Affiliations

  1. Department of Dermatology, Academic Medical Center, University of Amsterdam, 1100 DE, Amsterdam, The Netherlands

    Jan D. Bos

  2. Department of Dermatology, Netherlands Institute for Pigment Disorders, Academic Medical Center, University of Amsterdam, 1005 AZ Amsterdam, The Netherlands

    Rosalie M. Luiten

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  1. Jan D. Bos
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  1. Klinik für Dermatologie Venerologie und Allergologie, Charité - Universitätsklinikum Berlin Charite Campus Mitte Klinik und Poliklinik for Dermatologie, Charitéplatz 1, 10117 Berlin, Germany

    Eggert Stockfleth MD, PhD  & Claas Ulrich  & 

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Bos, J.D., Luiten, R.M. (2009). Skin Immune System. In: Stockfleth, E., Ulrich, C. (eds) Skin Cancer after Organ Transplantation. Cancer Treatment and Research, vol 146. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-78574-5_5

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  • DOI: https://doi.org/10.1007/978-0-387-78574-5_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-78573-8

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