Advertisement

Destructive Management of Skin Cancers in Organ Transplant Recipients

  • Jonathan Ng
  • Alvin Chong
  • Peter Foley
Part of the Cancer Treatment and Research book series (CTAR, volume 146)

Destructive therapies, namely cryotherapy and curettage and electrodessication (C&ED), play an important role in the day-to-day management of skin malignancies and premalignant lesions in the organ transplant recipient (OTR).

Keywords

Skin Cancer Basal Cell Carcinoma Thaw Cycle Actinic Keratose Organ Transplant Recipient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Thai KE, Sinclair RD. Crosurgery of benign skin lesions. Australas J Dermatol 1999; 40:175–86.PubMedCrossRefGoogle Scholar
  2. 2.
    Freeman M, Vinciullo C, Francis D, Spelman L, Nguyen R, Fergin P, Thai KE, Murrell D, Weightman W, Anderson C, Reid C, Watson A, Foley P. A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study. J Dermatol Treat 2003; 14:99–106.CrossRefGoogle Scholar
  3. 3.
    Thai KE, Fergin P, Freeman M, Vinciullo C, Francis D, Spelman L, Murrell D, Anderson C, Weightman W, Reid C, Watson A, Foley P. A prospective study of the use of cryosurgery for the treatment of actinic keratoses. Int J Dermatol 2004; 43:687–92.PubMedCrossRefGoogle Scholar
  4. 4.
    Sheridan AT, Dawber RP. Curettage, electrosurgery and skin cancer. Australas J Dermatol 2000; 41:19–30.PubMedCrossRefGoogle Scholar
  5. 5.
    Goldman G. The current status of curettage and electrodessication. Dermatol Clin 2002; 20:569–78.PubMedCrossRefGoogle Scholar
  6. 6.
    Clayton AS, Stasko T. Treatment of nonmelanoma skin cancer in organ transplant recipients: review of responses to a survey. J Am Acad Dermatol 2003; 49:413–16.PubMedCrossRefGoogle Scholar
  7. 7.
    Euvrard S, Kanitakis J, Claudy A. Skin cancers after organ transplantation. N Engl J Med 2003; 348:1681–91.PubMedCrossRefGoogle Scholar
  8. 8.
    Kokozska A, Scheinfeld N. Evidence-based review of the use of cryosurgery in treatment of basal cell carcinoma. Dermatol Surg 2003; 29:566–71.Google Scholar
  9. 9.
    Australian Cancer Network Management of Non-Melanoma Skin Cancer Working Party. Non-melanoma skin cancer: guidelines for treatment and management in Australia. 2002Google Scholar
  10. 10.
    Thissen M, Nieman F, Ideler A, Berretty P, Neumann H. Cosmetic results of cryosurgery versus surgical excision for primary uncomplicated basal cell carcinomas of the head and neck. Dermatol Surg 2000; 26:759–64.PubMedCrossRefGoogle Scholar
  11. 11.
    Wang I, Bendsoe N, Klinterberg C, Enejder A, Andersson-Engels S, Svanberg S, et al. Photodynamic therapy vs. cryosurgery of basal cell carcinomas: results of a phase III clinical trial. Br J Dermatol 2001; 144:832–40.PubMedCrossRefGoogle Scholar
  12. 12.
    Hall V, Leppard B, McGill J, Kesseler M, White J, Goodwin P. Treatment of basal-cell carcinoma: comparison of radiotherapy and cryotherapy. Clin Radiol 1986; 37:33–4.PubMedCrossRefGoogle Scholar
  13. 13.
    Basset-Seguin N Ibbotson S, Emtestam L, Tarstedt M, Morton C, Maroti M, et al. Topical methyl aminolaevulinate photodynamic therapy versus cryotherapy for superficial basal cell carcinoma: a 5 year randomised trail. Eur J Dermatol 2008; 18:547–53.PubMedGoogle Scholar
  14. 14.
    Kanitakis J, Alhaj-Ibrahim L, Euvrard S, Claudy A. Basal cell carcinomas developing in solid organ transplant recipients: clinicopathologic study of 176 cases. Arch Dermatol 2003; 139:1133–7.PubMedCrossRefGoogle Scholar
  15. 15.
    Mallon E, Dawber R. Cryosurgery in the treatment of basal cell carcinoma. Dermatol Surg 1996; 22:854–8.PubMedCrossRefGoogle Scholar
  16. 16.
    Stasko T, Brown MD, Carucci JA et al. Guidelines for the management of squamous cell carcinoma in organ transplant recipients. Dermatol Surg 2004; 30:642–50.PubMedCrossRefGoogle Scholar
  17. 17.
    Anonymous. European best practice guidelines for renal transplantation. Section IV. Long-term management of the transplant recipient. IV.6.2. Cancer risk after renal transplantation. Skin cancers: prevention and treatment. Nephrol Dial Transplant 2002; 17(Suppl 4):31–6.Google Scholar
  18. 18.
    Rosenblatt L, Marks R. Deaths due to squamous cell carcinoma in Australia: is there a case for a public health intervention? Australas J Dermatol 1996; 37:26–9.PubMedCrossRefGoogle Scholar
  19. 19.
    de Graaf YG, Basdew VR, van der Zwan-Kralt N, Willemze R, Bouwes Bavinck JN. The occurrence of residual or recurrent squamous cell carcinomas in organ transplant recipients after curettage and electrodesiccation. Br J Dermatol 2006; 154:493–7.PubMedCrossRefGoogle Scholar
  20. 20.
    Reymann F. Treatment of multiple squamous cell carcinomas of the skin in an immunosuppressed patient. Dermatologica 1981; 162:304–6.PubMedGoogle Scholar
  21. 21.
    Cooper JZ, Brown MD. Special concern about squamous cell carcinoma of the scalp in organ transplant recipients. Arch Dermatol. 2006; 142(6):755–8.PubMedCrossRefGoogle Scholar
  22. 22.
    Morton C, Horn M, Leman J, Tack B, Bedane C, Tjioe M, Ibbotson S, Khemis A, Wolf P. Comparison of topical methyl aminolevulinate photodynamic therapy with cryotherapy or fluorouracil for treatment of squamous cell carcinoma in situ: results of a multicenter randomized trial. Arch Dermatol 2006; 142(6):729–35.PubMedCrossRefGoogle Scholar
  23. 23.
    Ball S, Dawber R. Treatment of cutaneous Bowen’s disease with particular emphasis on the problem of lower leg lesions. Aust J Dermatol 1998; 39:63–70.CrossRefGoogle Scholar
  24. 24.
    Honeycutt WM, Jansen GT. Treatment of squamous cell carcinoma of the skin. Arch Dermatol 1973; 108:670–2.PubMedCrossRefGoogle Scholar
  25. 25.
    Berg D, Otley CC. Skin cancer in organ transplant recipients: epidemiology, pathogenesis, and management. J Am Acad Dermatol 2002; 47:1–17.PubMedCrossRefGoogle Scholar
  26. 26.
    Ulrich C, Schmook T, Nindl I, Meyer T, Sterry W, Stockfleth E. Cutaneous precancers in organ transplant recipients: an old enemy in a new surrounding. Br J Dermatol 2003; 149(Suppl 66):40–2.PubMedCrossRefGoogle Scholar
  27. 27.
    Orengo I, Brown T, Rosen T. Cutaneous neoplasia in organ transplant recipients. Curr Probl Dermatol 1999; 11:121–60.CrossRefGoogle Scholar
  28. 28.
    Lubritz RR, Smolewski SA. Cryosurgery cure rate of actinic keratoses. J Am Acad Dermatol 1982; 7:631–2.PubMedCrossRefGoogle Scholar
  29. 29.
    Fraunfelder FT, Farris HEJ, Wallace TR. Cryosurgery for ocular and periocular lesions. J Dermatol Surg Oncol 1977; 3:422–7.PubMedGoogle Scholar
  30. 30.
    Szeimies RM, Karrer S, Radakovic-Fijan S, Tanew A, Calzavara-Pinton PG, Zane C et al. Photodynamic therapy using topical methyl 5-aminolevulinate compared with cryotherapy for actinic keratosis: a prospective, randomized study. J Am Acad Dermatol 2002; 47(2):58–62.CrossRefGoogle Scholar
  31. 31.
    Ulrich C, Busch JO, Meyer T, Nindl I, Schmook T, Sterry W, Stockfleth E. Successful treatment of multiple actinic keratoses in organ transplant patients with topical 5% imiquimod: a report of six cases. Br J Dermatol 2006; 155(2):451–4.PubMedCrossRefGoogle Scholar
  32. 32.
    Traywick C, O’Reilly FM. Management of skin cancer in solid organ transplant recipients. Dermatol Ther 2005; 18:12–8.PubMedCrossRefGoogle Scholar
  33. 33.
    Holt PJ. Cruotherapy for skin cancer: results over a 5-year period using liquid nitrogen spray cryosurgery. Br J Dermatol 1988; 119:231–40.PubMedCrossRefGoogle Scholar
  34. 34.
    Nedwich JA. Evaluation of curettage and electrodesiccation in treatment of keratoacanthoma. Australas J Dermatol 1991; 32:137–41.PubMedCrossRefGoogle Scholar
  35. 35.
    Carucci JA. Squamous cell carcinoma in organ transplant recipients: approach to management. Skin Therapy Lett 2004; 9:5–7.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Jonathan Ng
    • 1
  • Alvin Chong
    • 2
  • Peter Foley
    • 3
  1. 1.Department of DermatologySt. Vincent’s Hospital Melbourne, Skin and Cancer FoundationVictoriaAustralia
  2. 2.Department of Medicine (Dermatology)St. Vincent’s Hospital Melbourne and Skin and Cancer Foundation Victoria, The University of MelbourneVictoriaAustralia
  3. 3.Department of Medicine (Dermatology)The University of Melbourne, St. Vincent’s Hospital MelbourneMelbourneAustralia

Personalised recommendations