Appendageal Malignancies

  • Catherine A. Harwood
  • Charlotte M. Proby
  • Rino Cerio
Part of the Cancer Treatment and Research book series (CTAR, volume 146)

Appendageal tumours (ATs) are neoplasms in which differentiation occurs toward one or more adnexal structures of the skin. The increased incidence, clinicopathologic spectrum and prognosis of keratinocyte skin cancers in organ transplant recipients (OTR) have all been well documented in recent years. In contrast, there are few publications relating to post-transplant ATs. Available reports provide evidence for a probable increased incidence of at least some of these neoplasms in OTRs. However, most published studies are essentially anecdotal observations or small case series, few data are available from systematic transplant cohort studies, and there is a dearth of reliable information on the prevalence of ATs in the general population. Such factors place major limitations on attempts to accurately assess relative risk of these tumours in OTRs.


Sebaceous Gland Merkel Cell Carcinoma Organ Transplant Recipient Sebaceous Carcinoma Sebaceous Adenoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Catherine A. Harwood
    • 1
    • 2
  • Charlotte M. Proby
    • 3
  • Rino Cerio
    • 4
  1. 1.Center for Cutaneous Research, Institute of Cell and Molecular ScienceBarts and The London School of Medicine and Dentistry, Queen Mary University of LondonLondon
  2. 2.Department of DermatologyBarts and the London NHS TrustLondonUnited Kingdom
  3. 3.Division of Surgery and OncologyCollege of Medicine, Dentistry and Nursing, University of Dundee, Ninewells HospitalDundeeUnited Kingdom
  4. 4.Departments of Dermatology and Pathology, Barts and The London NHS TrustInstitute of Cell and Molecular Science, Barts and The London School of Medicine and DentistryLondonUnited Kingdom

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