Ultraviolet-Induced Immunosuppression: Implications for Photocarcinogenesis

  • Stefan Beissert
  • Thomas Schwarz
Part of the Cancer Treatment and Research book series (CTAR, volume 146)

Ultraviolet (UV) irradiation can be regarded as one of the most significant environmental factors affecting human life. Although UV irradiation has an essential impact on terrestrial and aquatic ecology and is an essential requirement for the different life forms, particularly the mid wavelengths, UVB (290–320 nm), can also exert deleterious effects on health. The mechanisms underlying the influence of UV radiation on health are not limited to its instrumental role in the development of skin cancer, but also include the profound effects it has on local and systemic inflammatory responses. Analysing the biological effects of UVB irradiation has shown that UV exposure can significantly inhibit immunity.


Contact Hypersensitivity 
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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Stefan Beissert
    • 1
  • Thomas Schwarz
    • 2
  1. 1.Department of DermatologyUniversity Hospital Muenster48149 MuensterGermany
  2. 2.Department of DermatologyUniversity Hospital Schleswig-Holstein, Campus Kiel24105 KielGermany

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