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Tetrapyrroles pp 390-399 | Cite as

The Role of Heme d1 in Denitrification

  • Stuart J. Ferguson
Part of the Molecular Biology Intelligence Unit book series (MBIU)

Abstract

Heme d 1 is found only in a bacterial periplasmic enzyme, cytochrome cd 1, that catalyses reduction of nitrite to nitric oxide. The unique features of the d 1 heme include saturation of two of the pyrrole rings and presence of two carbonyl groups. Reasons for the selection of the d 1 ring for an enzyme catalysing this reaction are discussed and related to model compound studies. The problem of the biogenesis of the d 1 ring is outlined.

Keywords

Nitric Oxide Heme Iron Nitrite Reductase Ferrous State Nitrite Reduction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Landes Bioscience and Springer Science+Business Media 2009

Authors and Affiliations

  1. 1.Department of BiochemistryUniversity of OxfordOxfordUK

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