Stochastic Methods of Analysis

  • K.G. Manton
  • Igor Akushevich
  • Julia Kravchenko
Part of the Statistics for Biology and Health book series (SBH)


Many types of data are used to study carcinogenesis, e.g., data collected in case–control studies, tumor registries, follow-up data with covariate measurements made at regular, or irregular, time intervals, tracking of individual medical histories, and sample surveys. Data can also take the form of maps, where prevalence, incidence, or other quantities, characterizing the geographic distribution of cancer, is marked for administrative regions. These different forms of data require different statistical methods and models for their analysis.

Many population health models were developed by generalizing classical population and actuarial models. One of the first formal population models with an explicit biological rationale was the Bernoulli life table (see Chapter 4), used to describe the effects of the smallpox vaccination. The model was produced in 1825 by Benjamin Gompertz (1779–1865), a self-educated English mathematician, who became a fellow of the Royal Society, using...


Latent Class Model Negative Binomial Regression Model Microsimulation Model Ionize Radiation Dose Cancer Mortality Risk 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • K.G. Manton
    • 1
  • Igor Akushevich
    • 1
  • Julia Kravchenko
    • 1
  1. 1.Duke UniversityDurhamUSA

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