Immunosuppressive Agents

  • Manzoor M. Khan


Successful organ transplantation requires effective immunosuppression. Most of the modern advances in tissue transplantation have resulted from our precise understanding of the immune mechanisms involved in tissue rejection as well as from advances in surgical techniques to some degree. The last decade has witnessed the introduction of several potent immunosuppressive agents, which have led to considerable success in transplant medicine. The development of effective immunosuppressive therapy has been essential in tissue transplantation and for improvements in its positive outcome. Great advances have been made over the past 50 years in organ transplantation despite the complexities involved in immune suppression after tissue transplantation. The development of novel immunosuppressive agents has increased the graft survival rates; however, the side effects of these drugs resulting from their long-term use continue to present significant challenges. In addition to organ...


Acute Rejection Immunosuppressive Agent Mycophenolate Mofetil Calcineurin Inhibitor Antithymocyte Globulin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  1. 1.Creighton University Medical CenterOmahaUSA

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