Virulence Mechanisms of Acinetobacter
Definition of Pathogenicity
Pathogenicity is the ability of a microorganism to cause disease. Virulence is the pathogenicity degree of a microorganism that can vary between the members of a same species of pathogens. The virulence is not usually attributed to just one factor, but depends on various parameters related to the microorganism, the host, and the interaction between both (Winn Jr. et al., 2005). An infection begins when the balance between bacterial pathogenicity and host resistance is not stable (Peterson, 1996).
Pathogenicity of Acinetobacter
Until a few years ago, Acinetobacter was considered to be a relatively low-grade pathogen. However, the occurrence of fulminant community-acquired Acinetobacter pneumonia indicates that this bacterium may sometimes be of high pathogenicity and cause invasive disease (Joly-Guillou, 2005).
The genus Acinetobacterincludes aerobic Gram-negative coccobacilli that emerged as important opportunistic pathogens due to...
KeywordsQuorum Sensing Acinetobacter Baumannii Human Bronchial Epithelial Cell Virulence Mechanism Acinetobacter Strain
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