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Sepsis

  • Patricia Mello
  • R. Phillip Dellinger

Abstract

Sepsis represents the body’s response to an infectious insult. It is characterized by the dysregulation of the inflammatory response and of the coagulation homeostasis leading to a pro-inflammatory, prothrombotic, and antifibrinolysis state. Depending on the host’s predisposition and comorbidities, as well as on the nature and intensity of the insult, sepsis may progress to severe sepsis, which may be associated with circulatory shock, cellular dysfunction, multiple organ failure, and death.

Keywords

Septic Shock Severe Sepsis Mean Arterial Pressure Systemic Inflammatory Response Syndrome Septic Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Patricia Mello
    • 1
  • R. Phillip Dellinger
    • 2
  1. 1.Department of Critical Care, Hospital de Terapia IntensivaUniversidade Estadual Do PiauíTeresinaBrazil
  2. 2.Division of Critical Care Medicine, Robert Wood Johnson Medical SchoolCooper University Hospital, University of Medicine and Dentistry of New JerseyCamdenUSA

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