Sequencing Genes and Gene Islands by Gene Enrichment

  • Pablo D. Rabinowicz
  • W. Brad Barbazuk

Access to the sequence of any gene in a genome greatly accelerates genetics research. Whole genome sequencing is a way to retrieve such information although, for large genomes such as that of maize, it represents a huge effort. Fortunately, a maize genome sequencing project is currently underway but, before this project started, the maize research community benefited from the development of gene enrichment methods that allow selectively cloning and sequencing genes. The application of these methods to maize generated comprehensive gene sequence collections that were extensively used by the community. Once the maize genome project is completed, combination of gene enrichment methods with next-generation sequencing technologies will greatly facilitate genome-wide comparative analysis of different maize inbred lines for functional, population, and evolutionary studies.


Bacterial Artificial Chromosome Bacterial Artificial Chromosome Clone Repetitive Element Maize Genome Gene Enrichment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science + Business Media, LLC 2009

Authors and Affiliations

  1. 1.Institute for Genome Sciences and Department of Biochemistry and Molecular Biology, School of MedicineUniversity of MarylandBaltimore
  2. 2.Department of Botany and Zoology, and the Genetics InstituteUniversity of FloridaGainesville

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