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Pulsed Laser Deposition of Thin Calcium Phosphate Coatings

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Thin Calcium Phosphate Coatings for Medical Implants

Abstract

This chapter reviews the work performed by the international research community on the production of thin calcium phosphate (CaP) coatings by p`ulsed laser deposition (PLD). Studies on the mechanisms of the technique shed light on the scientific bases for optimization of the coatings beyond empirical work. The relations between the physicochemical coating properties and the various processing parameters are presented. PLD can produce extremely thin, dense, well adhering CaP coatings with extraordinary controlled chemistry and crystallinity. No postdeposition thermal annealing is needed. Different CaP phases and morphologies can be deposited, so the degree of resorption may be adapted to a specific medical application. Coatings with graded composition or graded crystallinity can readily be produced, not only on metal substrates but also on polymers. In vitro and in vivo testing with various cells and animal models have verified similar or better osseointegration of the PLD coatings compared to the commercially available plasma-sprayed coatings, with improved adhesion properties and without risk of delamination or detachment of the coating. The technique is mature enough for an industrial scale-up and the start of clinical tests with real dental or orthopedic implants.

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References

  1. H. M. Smith and A.F. Turner, Appl. Opt. 4 (1965) 147.

    Article  Google Scholar 

  2. D. Dijkkamp, Appl. Phys. Lett. 51 (1987) 619.

    Article  CAS  Google Scholar 

  3. M. Jarcho, Clin. Orthop. 157 (1981) 259.

    CAS  Google Scholar 

  4. R. Z. Legeros, Adv. Dent. Res. 2 (1988) 164.

    CAS  Google Scholar 

  5. K. De Groot, in “Bioceramics of Calcium Phosphate” edited by De Groot K. (CRC Press, Boca Raton, FL, USA, 1983) p. 100.

    Google Scholar 

  6. R. G. T. Geesink, K. De Groot, and C. P. A. T. Klein, J. Bone Joint Surg. 70-B (1988) 17.

    Google Scholar 

  7. R. D. Bloembaum and J. A. Dupond, J. Arthroplast. 8 (1993) 195.

    Article  Google Scholar 

  8. J. D. Bobyn, E. S. Mortimer, A. H. Glassman, C. A. Engh, J. E. Miller, and C. E. Brooks, Clin. Orthop. 261 (1992) 196.

    Google Scholar 

  9. W. L. Jaffe and D. F. Scott, J. Bone Joint Surg. 78-A (1996) 1918.

    Google Scholar 

  10. M. Okazaki, J. Takahashi, H. Kimura, and T. Aoba, J. Biomed. Mater. Res. 16 (1982) 851.

    Article  Google Scholar 

  11. M. J. Filiaggi, R. M. Pilliar, and N. A. Coombs, J. Biomed. Mater. Res. 27 (1993) 191.

    Article  CAS  Google Scholar 

  12. X. S. Zhang, P. A. Revell, S. L. Evans, M. A. Tuke, and P. J. Gregson, J. Biomed. Mater. Res. 46 (1999) 279.

    Article  CAS  Google Scholar 

  13. X. Zheng, M. Huang, and C. Ding, Biomaterials 21 (2000) 841.

    Article  CAS  Google Scholar 

  14. M. P. Ferraz, J. C. Knowles, J. Olsen, F. J. Monteiro, and J. D. Santos, Biomaterials 21 (2000) 813.

    Article  CAS  Google Scholar 

  15. P. Ducheyne, W. Van Raemdonck, J. C. Heughebaert, and M. Heughebaert, Biomaterials 7 (1986) 97.

    Article  CAS  Google Scholar 

  16. M. Yoshinari, Y. Ohtsuka, and T. Dérand, Biomaterials 15 (1994) 529.

    Article  CAS  Google Scholar 

  17. J. A. Jansen, J. G. Wolke, S. Swann, J. P. Van Der Waerden, and K. De Groot, Clin. Oral Implants Res. 4 (1993) 28.

    Article  CAS  Google Scholar 

  18. W. R. Lacefield, Ann. NY Acad. Sci. 523 (1988) 72.

    Article  CAS  Google Scholar 

  19. P. Li, J. Biomed. Mater. Res. 66A (2003) 79.

    Article  CAS  Google Scholar 

  20. C. M. Cotell, D. B. Chrisey, K. S. Grabowski, and J. A. Sprague, J. Appl. Biomater. 3 (1992) 87.

    Article  Google Scholar 

  21. P. Baeri, L. Torrisi, N. Marino, and G. Foti, Appl. Surf. Sci. 54 (1992) 210.

    Article  CAS  Google Scholar 

  22. G. Sardin, J. Palau, M. Varela, J. Esteve, and J. L. Morenza, in “Hydroxyapatite and related materials” edited by Brown P. W. and Constantz B. (CRC press, 1994) p. 225.

    Google Scholar 

  23. R. K. Singh, F. Qian, V. Nagabushnam, R. Damodaran, and B. M. Moudgil, Biomaterials 15 (1994) 522.

    Article  CAS  Google Scholar 

  24. P. Serra, J. Palau, M. Varela, J. Esteve, and J. L. Morenza, J. Mater. Res. 10 (1995) 473.

    Article  CAS  Google Scholar 

  25. M. Jelínek, V. Olsan, L. Jastrabík, V. Studnicka, V. Hnatowicz, J. Kvítek, V. Havránek, T. Dostálová, I. Zergioti, A. Petrakis, E. Hontzopoulos, and C. Fotakis, Thin Solid Films 257 (1995) 125.

    Article  Google Scholar 

  26. V. N. Bagratashvili, E. N. Antonov, E. N. Sobol, V. K. Popov, and S. M. Howdle, Appl. Phys. Lett. 66 (1995) 2451.

    Article  CAS  Google Scholar 

  27. B. E. Tucker, G. H. Nancollas, C. M. Cottell, R. C. Y. Auyeung, and M. Spector, Biomaterials 17 (1996) 631.

    Article  CAS  Google Scholar 

  28. S. Hontsu, M. Nakamori, H. Tabata, J. Ishii, and T. Kawai, Jpn. J. Appl. Phys. 35 (1996)

    Google Scholar 

  29. O. Guillot-Noël, R. Gómez-San Román, J. Perriére, J. Hermann, V. Craciun, C. Boulmer-Leborgne, and P. Barboux, J. Appl. Phys. 80 (1996) 1803.

    Article  Google Scholar 

  30. C. K. Wang, J. H. Chern Lin, C. P. Ju, H. C. Ong, and R. P. H. Chang, Biomaterials 18 (1997) 1331.

    Article  CAS  Google Scholar 

  31. J. L. Arias, M. B. Mayor, F. J. García-Sanz, J. Pou, B. León, M. Pérez-Amor, and J. C. Knowles, J. Mater. Sci. : Mater. Med. 8 (1997) 873.

    Article  CAS  Google Scholar 

  32. J. M. Fernández-Pradas, G. Sardin, L. Cléries, P. Serra, C. Ferrater, and J. L. Morenza, Thin Solid Films 317 (1998) 393.

    Article  Google Scholar 

  33. V. Craciun, I. W. Boyd, D. Craciun, P. Andreazza, and J. Perriere, J. Appl. Phys. 85 (1999) 8410.

    Article  CAS  Google Scholar 

  34. C. M. Cotell, Appl. Surf. Sci. 69 (1993) 140.

    Article  CAS  Google Scholar 

  35. L. Torrisi, Thin Solid Films 237 (1994) 12.

    Article  CAS  Google Scholar 

  36. L. Torrisi and R. Setola, Thin Solid Films 227 (1993) 32.

    Article  CAS  Google Scholar 

  37. E. N. Antonov, V. N. Bagratashvili, V. K. Popov, E. N. Sobol, S. M. Howdle, C. Joiner, K. G. Parker, T. L. Parker, A. A. Doktorov, V. B. Likhanov, A. I. Volozhin, S. S. Alimpiev, and S. M. Nikiforov, J. Biomed. Optics 3 (1998) 423.

    Article  CAS  Google Scholar 

  38. R. Kelly and A. Miotello, in “Pulsed Laser Deposition of Thin Films” edited by Chrisey D. B. and Hubler G. H. (John Wiley & Sons, New York, 1994) p. 55.

    Google Scholar 

  39. D. B. Geohegan, in “Pulsed Laser Deposition of Thin Films” edited by Chrisey D. B. and Hubler G. H. (John Wiley & Sons, New York, 1994) p. 115.

    Google Scholar 

  40. J. S. Horwitz and J. A. Sprague, in "Pulsed Laser Deposition of Thin Films" edited by Chrisey D. B. and Hubler G.H. (John Wiley & Sons, New York, 1994) p. 229.

    Google Scholar 

  41. B. Feddes, A. M. Vredenberg, M. Wehner, J. C. G. Wolke, and J. A. Jansen, Biomaterials 26 (2005) 1645.

    Article  CAS  Google Scholar 

  42. H. Zeng, W. R. Lacefield, and S. Mirov, J. Biomed. Mater. Res. 50 (2000) 248.

    Article  CAS  Google Scholar 

  43. F. J. García-Sanz, M. B. Mayor, J. L. Arias, J. Pou, B. León, and M. Pérez-Amor, J. Mater. Sci.: Mater. Med. 8 (1997) 861.

    Article  Google Scholar 

  44. J. M. Fernández-Pradas, L. Cléries, G. Sardin, and J. L. Morenza, Biomaterials 23 (2002) 1989.

    Article  Google Scholar 

  45. J. L. Arias, PhD thesis (University of Vigo, Spain, 2000).

    Google Scholar 

  46. E. Masetti, M. Jelínek, and C. Grivas, Proc. SPIE 2965 (1996) 128.

    Article  CAS  Google Scholar 

  47. J. M. Fernández-Pradas, PhD thesis (University of Barcelona, Spain, 1999).

    Google Scholar 

  48. O. Blind, B. Dailey, L. Jordan, and L. H. Klein, Dent. Mater. 21 (2005) 1017.

    Article  CAS  Google Scholar 

  49. J. L. Arias, F. J. García-Sanz, M. B. Mayor, S. Chiussi, J. Pou, B. León, and M. Pérez-Amor, Biomaterials 19 (1998) 883.

    Article  CAS  Google Scholar 

  50. M. Katto, K. Kurosawa, A. Yokotani, S. Kubodera, A. Kameyama, T. Higashiguchi, T. Nakayama, and M. Tsukamoto, Appl. Surf. Sci. 248 (2005) 365.

    Article  CAS  Google Scholar 

  51. D. Ferro, J. V. Rau, S. M. Barinov, R. Teghil, and A. Latini, Biomaterials 26 (2005) 805.

    Article  CAS  Google Scholar 

  52. M. P. Ferraz, F. J. Monteiro, D. Giao, B. León, P. González, S. Liste, J. Serra, J. Arias, and M. Pérez-Amor, Key Eng. Mater. 254–256 (2004) 347.

    Article  Google Scholar 

  53. E. L. Solla, J. P. Borrajo, P. González, J. Serra, S. Chiussi, B. León, and J. García-López, Appl. Surf. Sci. 253 (2006) 8282.

    Google Scholar 

  54. E. Gyorgy, G. Socol, M. Iliescu, I. N. Mihailescu, P. Toricelli, J. Werckman, I. Mayer, and A. Bigi, J. Biomed. Mater. Res. A 71A (2004) 353.

    Article  CAS  Google Scholar 

  55. Y. Suda, H. Kawasaki, T. Ohshima, S. Nakashima, S. Kawazoe, and T. Toma, Thin Solid Films 506–507 (2006) 115.

    Article  CAS  Google Scholar 

  56. P. Serra and J. L. Morenza, Thin Solid Films 335 (1998) 43.

    Article  CAS  Google Scholar 

  57. P. Serra and J. L. Morenza, Appl. Surf. Sci. 127–129 (1998) 662.

    Article  Google Scholar 

  58. P. Serra, J. M. Fernández-Pradas, G. Sardin, and J. L. Morenza, Appl. Surf. Sci. 109–110 (1997).

    Google Scholar 

  59. P. Serra, L. Cléries, and J. L. Morenza, Appl. Surf. Sci. 96–98 (1996) 216.

    Article  Google Scholar 

  60. P. Serra, J. M. Fernández-Pradas, J. Navarro, and J. L. Morenza, Appl. Phys. A 69 (1999)

    Google Scholar 

  61. J. L. Arias, M. B. Mayor, J. Pou, B. León, and M. Pérez-Amor, Appl. Surf. Sci. 186 (2002) 448.

    Article  CAS  Google Scholar 

  62. J. L. Arias, M. B. Mayor, J. Pou, B. León, and M. Pérez-Amor, Appl. Surf. Sci. 208–209 (2003) 57.

    Article  CAS  Google Scholar 

  63. D. G. A. Nelson and J. D. B. Featherstone, Calcif. Tiss. Int. 34 (1982) 69.

    CAS  Google Scholar 

  64. R. Z. Legeros, O. R. Trautz, J. P. Legeros, and E. Klein, Bull. Soc. Chim.(Fr.) special issue (1968) 1712.

    Google Scholar 

  65. H. Zeng and W. R. Lacefield, Biomaterials 21 (2000) 23.

    Article  CAS  Google Scholar 

  66. J. L. Arias, M. B. Mayor, J. Pou, B. León, and M. Pérez-Amor, Appl. Surf. Sci. 154 (2000) 434.

    Article  Google Scholar 

  67. E. N. Antonov, V. N. Bagratashvili, L. I. Krotova, V. K. Popov, M. Ball, S. Downes, D. M. Grant, S. M. Howdle, and W. J. Lo, Key Eng. Mater. 192–195 (2001) 107.

    Article  Google Scholar 

  68. J. M. Fernández-Pradas, L. Cléries, P. Serra, G. Sardin, and J. L. Morenza, Appl. Phys. A 72 (2001) 613.

    Article  Google Scholar 

  69. P. Serra and J. L. Morenza, J. Appl. Phys. 85 (1999) 3289.

    Article  CAS  Google Scholar 

  70. J. M. Fernández-Pradas, G. Sardin, and J. L. Morenza, Appl. Phys. A 76 (2003) 251.

    Article  CAS  Google Scholar 

  71. J. L. Arias, M. B. Mayor, J. Pou, B. León, and M. Pérez-Amor, Vacuum. 67 (2002) 653.

    Article  CAS  Google Scholar 

  72. M. B. Mayor, J. Arias, S. Chiussi, F. Garcia, J. Pou, B. León, and M. Pérez-Amor, Thin Solid Films 317 (1998) 363.

    Article  CAS  Google Scholar 

  73. E. Jiménez, J. L. Arias, B. León, and M. Pérez-Amor, Thin Solid Films 453–454 (2004) 422.

    Article  CAS  Google Scholar 

  74. J. Arends and W. L. Jongebloed, Recl. Trav. Chim. Pays-Bas 100 (1981) 3.

    Article  CAS  Google Scholar 

  75. M. B. Mayor, PhD thesis (University of Vigo, Spain, 2000).

    Google Scholar 

  76. R. Z. Legeros and J. P. Legeros, in “An introduction to bioceramics” edited by Hench L.L. and Wilson J. (World Scientific, 1993) p. 139.

    Google Scholar 

  77. J. M. Fernández-Pradas, M. V. García-Cuenca, and J. L. Morenza, Appl. Phys. A 80 (2005) 325.

    Article  CAS  Google Scholar 

  78. E. Jiménez, J. L. Arias, B. León, and M. Pérez-Amor, Key Eng. Mater. 254–256 (2004) 415.

    Article  Google Scholar 

  79. M. Iliescu, J. Werckmann, V. Nelea, I. N. Mihailescu, G. Socol, A. Bigi, and B. Bracci, Thin Solid Films 453–454 (2004) 157.

    Article  CAS  Google Scholar 

  80. G. Socol, F. Miroiu, I. N. Mihailescu, P. Torricelli, B. Bracci, A. Bigi, M. Iliescu, and J. Werckmann, Biomaterials 25 (2004) 2539.

    Article  CAS  Google Scholar 

  81. E. N. Antonov, V. N. Bagratashvili, V. K. Popov, M. D. Ball, D. M. Grant, S. M. Howdle, and C. A. Scotchford, J. Mater. Sci. : Mater. Med. 14 (2003) 151.

    Article  CAS  Google Scholar 

  82. S. Hontsu, T. Matsumoto, J. Ishii, M. Nakamori, H. Tabata, and T. Kawai, Thin Solid Films 295 (1997) 214.

    Article  CAS  Google Scholar 

  83. M. Kusunoki, M. Kawasima, H. Nishikawa, K. Morimoto, T. Hayami, S. Hontsu, and T. Kawai, Jpn. J. Appl. Phys. 2 44 (2005)

    Google Scholar 

  84. E. N. Antonov, V. N. Bagratashvili, L. I. Krotova, and V. K. Popov, in Proceedings of the 13th International Symposium on Ceramics in Medicine, edited by Giannini S. and Moroni A. (Trans Tech Publications, Bologne, Italy, 2001).

    Google Scholar 

  85. M. D. Ball, S. Downes, C. A. Scotchford, E. N. Antonov, V. N. Bagratashvili, V. K. Popov, W. J. Lo, D. M. Grant, and S. M. Howdle, Biomaterials 22 (2001) 337.

    Article  CAS  Google Scholar 

  86. J. P. Borrajo, J. Serra, S. Liste, P. González, S. Chiussi, B. León, and M. Pérez-Amor, Appl. Surf. Sci. 248 (2005) 355.

    Article  CAS  Google Scholar 

  87. V. Nelea, H. Pelletier, M. Iliescu, J. Werckmann, V. Craciun, I. N. Mihailescu, C. Ristoscu, and C. Ghica, J. Mater. Sci. : Mater. Med. 13 (2002) 1167.

    Article  CAS  Google Scholar 

  88. M. Katto, M. Nakamura, T. Tanaka, and T. Nakayama, Appl. Surf. Sci. 197–198 (2002) 768.

    Article  Google Scholar 

  89. M. Katto, M. Nakamura, T. Tanaka, T. Matsutani, M. Kuwata, and T. Nakayama, Surf. Coat. Tech. 169–170 (2003) 712.

    Article  CAS  Google Scholar 

  90. E. L. Solla, J. P. Borrajo, P. González, J. Serra, S. Liste, S. Chiussi, B. León, and M. Pérez-Amor, Appl. Surf. Sci. 248 (2005) 360.

    Article  CAS  Google Scholar 

  91. P. J. Burnett and D. S. Rickerby, Thin Solid Films 157 (1988) 233.

    Article  CAS  Google Scholar 

  92. Y. Yang and J. L. Ong, J. Biomed. Mater. Res. A 64 (2003) 509.

    Article  CAS  Google Scholar 

  93. L. Cléries, E. Martínez, J. M. Fernández-Pradas, G. Sardin, J. Esteve, and J. L. Morenza, Biomaterials 21 (2000) 967.

    Article  Google Scholar 

  94. J. M. Fernández-Pradas, L. Cléries, Martínez E., G. Sardin, J. Esteve, and J. L. Morenza, Biomaterials 22 (2001) 2171.

    Article  Google Scholar 

  95. J. L. Arias, M. B. Mayor, J. Pou, B. León, M. Pérez-Amor, and Y. Leng, Biomaterials 24 (2003) 3403.

    Article  CAS  Google Scholar 

  96. J. M. Fernández-Pradas, M. V. García-Cuenca, L. Cléries, G. Sardin, and J. L. Morenza, Appl. Surf. Sci. 195 (2002) 31.

    Article  Google Scholar 

  97. C. G. Zhang, M. F. Cheng, Y. Leng, P. Tong, and J. Y. Chen, in Biomedical Materials Research in the Far East (III), edited by Zhang Z. and Ikada Y. (Kobushi Kantokai Inc, Kyoto, 1997).

    Google Scholar 

  98. V. Nelea, H. Pelletier, P. Mille, V. Craciun, I. N. Mihailescu, M. Iliescu, and J. Werckmann, Appl. Surf. Sci. 208–209 (2003) 638.

    Article  CAS  Google Scholar 

  99. V. Nelea, H. Pelletier, P. Mille, and D. Muller, Thin Solid Films 453–454 (2004) 208.

    Article  CAS  Google Scholar 

  100. L. Cléries, J. M. Fernández-Pradas, G. Sardin, and J. L. Morenza, Biomaterials 19 (1998) 1483.

    Article  Google Scholar 

  101. L. Cléries, J. M. Fernández-Pradas, G. Sardin, and J. L. Morenza, Biomaterials 20 (1999) 1401.

    Article  Google Scholar 

  102. J. L. Arias, J. Pou, B. León, C. Peraire, and A. Arañó, in Transactions – 7th World Biomaterials Congress, edited by Howlett R. (Australian Society for Biomaterials Inc., Sydney, 2004).

    Google Scholar 

  103. C. Peraire, A. Rovira, A. Araño, B. Mayor, J. L. Arias, J. Pou, and B. León, Report (EU CRAFT project: BRE2.CT94.1533, 1997).

    Google Scholar 

  104. T. L. Parker, K. G. Parker, S. M. Howdle, E. N. Antonov, V. N. Bagratashvili, V. K. Popov, E. Sobol, and C. J. Roberts, Cell Eng. 1 (1996) 91.

    Google Scholar 

  105. L. Cléries, J. M. Fernández-Pradas, and J. L. Morenza, J. Biomed. Mater. Res. 49 (2000) 43.

    Article  Google Scholar 

  106. J. D. De Bruijn, J. E. Davies, and C. A. Van Blitterswijk, J. Biomed. Mater. Res. 29 (1995) 89.

    Article  Google Scholar 

  107. J. E. Davies, Anat. Rec. 245 (1996) 426.

    Article  CAS  Google Scholar 

  108. J. Morgan, K. R. Holtman, J. C. Keller, and C. M. Stanford, Implan. Dent. 6 (1996) 264.

    Article  Google Scholar 

  109. H. Matsuoka, H. Akiyama, Y. Okada, H. Ito, C. Shigeno, J. Konishi, T. Kokubo, and T. Nakamura, J. Biomed. Mater. Res. 47 (1999) 176.

    Article  CAS  Google Scholar 

  110. L. Himmlová, T. Dostálová, M. Jelínek, J. Bártová, V. Pesáková, and M. Adam, Proc. SPIE 3564 (1998) 221.

    Google Scholar 

  111. M. Seydlova, Z. Teuberova, T. Dostálová, B. Dvorankova, K. Smetana, M. Jelínek, T. Kocourek, and W. Mróz, J. Appl. Phys. 99 (2006) 014905.

    Article  CAS  Google Scholar 

  112. A. Bigi, B. Bracci, L. Sturba, F. Cuisinier, R. Elkaim, M. Fini, P. Torricelli, I. Mayer, I. N. Mihailescu, and G. Socol, Biomaterials 26 (2005) 2381.

    Article  CAS  Google Scholar 

  113. C. M. Cotell, J. A. Conklin, R. C. Y. Auyeung, S. S. Wong, C. M. Klapperich, and M. Spector, Mater. Res. Soc. Symp. Proc. 414 (1996) 171.

    Article  CAS  Google Scholar 

  114. T. Dostálová, M. Jelínek, L. Himmlová, and C. Grivas, Proc. SPIE 3593 (1999) 81.

    Article  Google Scholar 

  115. T. Dostálová, L. Himmlová, M. Jelínek, and C. Grivas, Laser Phys. 8 (1998) 182.

    Google Scholar 

  116. M. Jelínek, T. Dostálová, L. Himmlová, C. Grivas, and C. Fotakis, Mol. Cryst. Liq. Cryst. Sci. Tech. A Mol. Cryst. Liq. Cryst. 374 (2002) 599.

    Google Scholar 

  117. T. Dostálová, L. Himmlová, M. Jélinek, and C. Grivas, J. Biomed. Optics 6 (2001) 239.

    Article  Google Scholar 

  118. C. Peraire, J. Arias, D. Bernal, J. Pou, B. León, A. Arañó, and W. Roth, J. Biomed. Mater. Res. 77A (2006) 370.

    Article  CAS  Google Scholar 

  119. C. Peraire, A. Arañó, A. Arsuaga, B. Assenza, A. Borrell, A. Padrós, J. L. Arias, J. Pou, and B. León, Final report (EU CRAFT Project: BRE2. CT94. 1533, 1997).

    Google Scholar 

  120. D. Lew, A. A. Marino, J. M. Startzell, and J. C. Keller, J. Oral Maxillofac. Surg. 52 (1994) 952.

    Article  CAS  Google Scholar 

  121. S. Mohammadi, M. Esposito, L. Emanuelsson, and P. Thomsen, in Transactions- 7th World Biomaterials Congress, edited by Howlett R. (Australian Society for Biomaterials Inc., Sydney, 2004).

    Google Scholar 

  122. S. Mohammadi, M. Esposito, L. Emanuelsson, and P. Thomsen, in Transactions- 7th World Biomaterials Congress, edited by Howlett R. (Australian Society for Biomaterials Inc., Sydney, 2004).

    Google Scholar 

  123. J. A. Greer, in “Pulsed Laser Deposition of Thin Films” edited by Chrisey D. B. and Hubler G. H. (John Wiley & Sons, Inc., New York, 1994) p. 293.

    Google Scholar 

  124. J. M. Fernández-Pradas, L. Cléries, E. Martínez, G. Sardin, J. Esteve, and J. L. Morenza, Appl. Phys. A A71 (2000) 37.

    Google Scholar 

  125. S. Hontsu, J. Ishii, M. Nakamori, N. Kato, T. Matsumoto, H. Tabata, and T. Kawai, Jpn. J. Appl. Phys. 2 37 (1998)

    Google Scholar 

  126. L. L. Hench and J. Wilson, in “An Introduction to Bioceramics” edited by Hench L. L. and Wilson J. (World Scientific, Singapore, 1993) p. 1.

    Chapter  Google Scholar 

  127. E. N. Antonov, V. N. Bagratashvili, V. K. Popov, E. N. Sobol, and S. M. Howdle, Spectrochimica Acta Part A 52A (1996) 123.

    Article  CAS  Google Scholar 

  128. E. N. Antonov, V. N. Bagratashvili, V. K. Popov, E. N. Sobol, M. C. Davies, S. J. B. Tendler, C. J. Roberts, and S. M. Howdle, Biomaterials 18 (1997) 1043.

    Article  CAS  Google Scholar 

  129. F. García, J. L. Arias, B. Mayor, J. Pou, B. León, M. Pérez-Amor, I. Rehman, J. Knowles, S. Best, and W. Bonfield, J. Biomed. Mater. Res. 43 (1998) 69.

    Article  Google Scholar 

  130. M. B. Mayor, J. L. Arias, F. J. García-Sanz, S. Chiussi, J. Pou, B. León, and M. Pérez-Amor, Biomaterials 11 (1998) 209.

    CAS  Google Scholar 

  131. P. Serra and J. L. Morenza, Appl. Phys. A 67 (1998) 289.

    Article  CAS  Google Scholar 

  132. V. Craciun, D. Craciun, P. Andreazza, J. Perriere, and I. W. Boyd, Appl. Surf. Sci. 138 (1999) 587.

    Article  Google Scholar 

  133. L. Cléries, J. M. Fernández-Pradas, and J. L. Morenza, Biomaterials 21 (2000) 1861.

    Article  Google Scholar 

  134. W. J. Lo, D. M. Grant, B. S. Welsh, M. D. Ball, S. M. Howdle, E. N. Antonov, V. N. Bagratashvili, and V. K. Popov, J. Biomed. Mater. Res. 50 (2000) 536.

    Article  CAS  Google Scholar 

  135. V. Nelea, H. Pelletier, P. Mille, A. Cornet, C. Ristoscu, C. Chiritescu, I. N. Mihailescu, and C. Ghica, Appl. Surf. Sci. 168 (2000) 127.

    Article  CAS  Google Scholar 

  136. H. Zeng and W. R. Lacefield, J. Biomed. Mater. Res. 50 (2000) 239.

    Article  CAS  Google Scholar 

  137. V. Nelea, H. Pelletier, D. Muller, N. Broll, P. Mille, C. Ristoscu, and I. N. Mihailescu, Appl. Surf. Sci. 186 (2002) 483.

    Article  CAS  Google Scholar 

  138. P. N. De Aza, J. M. Fernández-Pradas, and P. Serra, Biomaterials 25 (2004) 1983.

    Article  CAS  Google Scholar 

  139. M. Iliescu, J. Werckmann, V. Nelea, and I. N. Mihailescu, Surf. Coat. Tech. 187 (2004) 131.

    Article  CAS  Google Scholar 

  140. V. Nelea, C. Morosanu, M. Iliescu, and I. N. Mihailescu, Appl. Surf. Sci. 228 (2004) 346.

    Article  CAS  Google Scholar 

  141. L. C. Nistor, C. Ghica, V. S. Teodorescu, S. V. Nistor, M. Dinescu, D. Matei, N. Frangis, N. Vouroutzis, and C. Liutas, Mater. Res. Bull. 39 (2004) 2089.

    Article  CAS  Google Scholar 

  142. H. Pelletier, V. Nelea, P. Mille, and D. Muller, J. Mater. Sci. 39 (2004) 4185.

    Article  CAS  Google Scholar 

  143. H. Pelletier, V. Nelea, P. Mille, and D. Muller, J. Mater. Sci. 39 (2004) 3605.

    Article  CAS  Google Scholar 

  144. H. Pelletier, V. Nelea, P. Mille, and D. Muller, Nucl. Instr. and Meth. in Phys. Res. B 216 (2004) 269.

    Article  CAS  Google Scholar 

  145. H. Pelletier, V. Nelea, P. Mille, and D. Muller, Nucl. Instr. and Meth. in Phys. Res. B 216 (2004) 275.

    Article  CAS  Google Scholar 

  146. J. Beltrano, L. Torrisi, and D. Margarone, Radiation Effects and Defects in Solids 160 (2005) 545.

    Article  CAS  Google Scholar 

  147. J. P. Borrajo, J. Serra, S. Liste, P. González, S. Chiussi, B. León, and M. Pérez-Amor, Appl. Surf. Sci. 248 (2005) 355.

    Article  CAS  Google Scholar 

  148. H. Kim, R. P. Camata, Y. K. Vohra, and W. R. Lacefield, J. Mater. Sci. : Mater. Med. 16 (2005) 961.

    Article  CAS  Google Scholar 

  149. I. N. Mihailescu, G. Socol, F. Miroiu, P. Torricelli, A. Bigi, I. Mayer, M. Iliescu, J. Werckmann, F. Cuisinier, R. Elkaim, and G. Hildebrand, Appl. Surf. Sci. 248 (2005) 344.

    Article  CAS  Google Scholar 

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Acknowledgments

The work performed at the University of Vigo could not have been possible without the valuable contributions of present and past coworkers: J.L. Arias, M.B. Mayor, F. García, E. Jiménez, J. Pou, S. Chiussi, P. González, J. Serra, J.P. Borrajo, S. Liste, E. Solla, M. Pérez-Amor, C. Peraire, D. Bernal, and A. Arañó. I would like to express my gratitude to all of them. Some fruitful discussions with F. Driessens have stimulated our activities. P. Kitajlowicz has technically helped with the manuscript. Financial support of CICYT (MAT93-0271, DPI2000-0393-P4-04 MAT2003-09277-C03-01), UE CRAFT (BRE2.CT94.1533), MINER (PATI 665/95), Xunta de Galicia (INFRA93, INFRA94-58, INFRA96-ED405A-50 and C. Educación 200612), and the University of Vigo is acknowledged.

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  1. Departmento de Física Aplicada, E.T.S.I. Industriales, University of Vigo, Lagoas-Marcosende s/n, 36200 Vigo, Spain

    Betty León

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    León, B. (2009). Pulsed Laser Deposition of Thin Calcium Phosphate Coatings. In: León, B., Jansen, J. (eds) Thin Calcium Phosphate Coatings for Medical Implants. Springer, New York, NY. https://doi.org/10.1007/978-0-387-77718-4_5

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