Solar UV Exposure and Mortality from Skin Tumors
Solar ultraviolet radiation (UVR) exposure is clearly associated with increased mortality from nonmelanoma skin cancer—usually squamous cell carcinoma. However, the association with cutaneous melanoma is unclear from the evidence in ecologic studies and the few analytic studies show that high levels of intermittent UV exposure prior to diagnosis are somehow associated with improved survival from melanoma. Understanding this conundrum is critical to present coherent public health messages and to improve the mortality rates from melanoma.
KeywordsSkin Cancer Nonmelanoma Skin Cancer Solar Ultraviolet Radiation Melanoma Skin Cancer Solar Elastosis
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- 3.Grant WB. An ecologic study of cancer mortality in Spain with respect to indices of solar UVB irradiance and smoking. International Journal of Epidemiology 120(5):1123–1128.Google Scholar
- 6.Armstrong BK. Ch 6. Epidemiology of melanoma and current trends. In Textbook of Melanoma, London; Martin Dunitz 2006; 65–80.Google Scholar
- 7.Lachiewicz AM, Berwick M, Wiggins CL et al. N Survival Differences between Scalp/Neck Melanoma and Melanoma of Other Sites in the Surveillance, Epidemiology and End Results (SEER) Program (In preparation).Google Scholar
- 14.Morales Suarez-Varela M, Llopis-Gonzalez A, Lacasana-Navarro M et al. Trends in malignant skin melanoma and other skin cancers in Spain, 1975–1983 and their relation to solar radiation intensity. Journal Environmental Pathology, Toxicology, Oncology 1990; 10:245–253.Google Scholar
- 15.Gass R, Bopp M. Mortality from malignant melanoma: epidemiological trends in Switzerland. Schweiz Rundsch Med Prax 2005; 94:1295–300.Google Scholar
- 21.Fears et al.Google Scholar
- 23.Larsen TE, Grude TH. A retrospective histological study of 669 cases of primary cutaneous malignant melanoma in clinical stage I. 6. The relation of dermal solar elastosis to sex, age and survival of the patient and to localization, histological type and level of invasion of the tumour. Acta Pathol Microbiol Scand 1979; 87A:361–366.Google Scholar
- 26.Zanetti R, Rosso S and the Helios Study. Sun exposure habits in an Italian population and survival from melanoma (In preparation).Google Scholar