Disorders of Thermoregulation

  • Frederic H. Kauffman
  • Joanne E. Hullings


After studying this chapter, you should be able to: Discuss the major mechanisms of normal thermoregulation. Define heatstroke and list predisposing factors. Describe the clinical manifestations of heatstroke and its treatment modalities and goals. List the major factors that affect prognosis in heatstroke. Define malignant hyperthermia and list the ways in which it differs from heatstroke. Define hypothermia and differentiate the general clinical manifestations associated with declining core temperature. Describe various clinical procedures used to lower core temperature. Know the clinical significance of core temperature afterdrop, the situations in which it occurs, and ways to avoid it. Interpret arterial blood gas (ABG) results in a clinically useful manner.


Heat Stress Core Temperature Disseminate Intravascular Coagulation Core Body Temperature Malignant Hyperthermia 
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Additional Reading

  1. Danzl DF, Pozos RS. Accidental hypothermia. N Engl J Med. 1994;331:1756-1760.PubMedCrossRefGoogle Scholar
  2. Delaney KA, Vassallo SU. Thermoregulatory principles. In: Flomenbaum NE, Goldfrank LR, Hoffman R, et al., eds. Goldfrank’s Toxicologic Emergencies. New York: McGraw Hill; 2006.Google Scholar
  3. Kauffman FH. Profound accidental hypothermia. Trauma Q. 1989;6:7-11.Google Scholar
  4. Lugo-Amador NM, Rothenhaus T, Moyer P. Heat related illness. Emerg Med Clin North Am. 2004;22:315-327.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Frederic H. Kauffman
    • 1
  • Joanne E. Hullings
    • 2
  1. 1.Departments of Emergency Medicine and MedicineTemple University School of MedicinePhiladelphiaUSA
  2. 2.Department of Emergency MedicineTemple University School of MedicinePhiladelphiaUSA

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