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Quantification of Improved Left Ventricular Performance during Cardiac Resynchronization Therapy

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Intensive Care Medicine

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Abstract

Regional contraction asynchrony is the most common contractile abnormality seen clinically, accounting for much of the observed, clinically relevant increase in morbidity from heart disease. Regional myocardial dyssynchrony, characterized by regional wall motion abnormalities (RWMA), commonly occurs in patients with both normal [1–4] and abnormal [5–7] cardiac physiology. RWMA are monitored intraoperatively to detect regional myocardial ischemia [8–10]. The impact of RWMA on global left ventricular (LV) performance is difficult to quantify but it is important to have a quantitative measure of regional myocardial dysfunction to minimize subjective bias in the diagnosis of myocardial ischemia [2], and aid in the evaluation of treatments and titration of therapies used to restore regional myocardial function, including both revascularization and cardiac resynchronization therapy.

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Author information

Authors and Affiliations

  1. Department of Critical Care Medicine, University of Pittsburgh Medical Center, 606 Scaife Hall 3550 Terrace Street, Pittsburgh, PA, 15261, USA

    B. Lamia & M. R. Pinsky

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  1. B. Lamia
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  2. M. R. Pinsky
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Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Université libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium

    Jean-Louis Vincent MD, PhD, FCCM, FCCP (Head) (Head)

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Lamia, B., Pinsky, M.R. (2008). Quantification of Improved Left Ventricular Performance during Cardiac Resynchronization Therapy. In: Vincent, JL. (eds) Intensive Care Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-77383-4_7

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  • DOI: https://doi.org/10.1007/978-0-387-77383-4_7

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-77382-7

  • Online ISBN: 978-0-387-77383-4

  • eBook Packages: MedicineMedicine (R0)

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