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Early Optimization of Oxygen Delivery in High-risk Surgical Patients

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Book cover Intensive Care Medicine

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Abstract

Total tissue perfusion relies on adequate arterial oxygen saturation, cardiac output, and hemoglobin concentration, and global perfusion is usually assessed by calculation of the oxygen delivery index (DO2I) [1]. More than 20 years ago Shoemaker et al. reported that perioperative alterations in DO2 were closely correlated to the development of multiple organ failure (MOF) and death [2]. Since then goal-directed therapy, defined as the use of the cardiac output or a surrogate to guide intravenous fluid and inotropic therapy, has been used in an attempt to improve outcome in surgical patients [1].

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Author information

Authors and Affiliations

  1. Division of Critical Care Medicine Department of Internal Medicine, Medical School-FUNFARME and Hospital de Base, Rua Antonio de Godoy 3548 Centro Sao José do Rio Preto - SP, 15015-100, Brazil

    S. M. Lobo

  2. Intensive Care Department, Hospital do Servidor Publico Estadual, Rua Pedro de Toledo 1800, Sao Paulo, 040039901, Brazil

    E. Rezende

  3. Intensive Care Unit, Hospital Sao Lucas da PUCRS, Av. Ipiranga 6690, Porto Alegre, 90610-000, Brazil

    F. Suparregui Dias

Authors
  1. S. M. Lobo
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  2. E. Rezende
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  3. F. Suparregui Dias
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Editor information

Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Université libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium

    Jean-Louis Vincent MD, PhD, FCCM, FCCP (Head) (Head)

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Lobo, S.M., Rezende, E., Suparregui Dias, F. (2008). Early Optimization of Oxygen Delivery in High-risk Surgical Patients. In: Vincent, JL. (eds) Intensive Care Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-77383-4_61

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  • DOI: https://doi.org/10.1007/978-0-387-77383-4_61

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-77382-7

  • Online ISBN: 978-0-387-77383-4

  • eBook Packages: MedicineMedicine (R0)

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