Cortisol Metabolism in Inflammation and Sepsis
Steroid therapy has not been consistently shown to provide benefit in severe sepsis and may even be associated with adverse effects. The driver for steroid therapy is based on the controversial and unproven premise that there is relative adrenal insufficiency (based on a blunted cortisol response to corticotropin) in septic shock .
KeywordsSeptic Shock Chronic Fatigue Syndrome Glycyrrhetinic Acid Relative Adrenal Insufficiency Total Cortisol
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