The Role of Hypoxia and Inflammation in the Expression and Regulation of Proteins Regulating Iron Metabolism

  • S. Brandt
  • J. Takala
  • P. M. Lepper
Conference paper


Sepsis is a leading cause of morbidity and mortality in western countries. Sepsisrelated inflammation causes micro circulatory dysfunction, inadequate tissue oxygen supply, and cellular and subcellular function disturbances including mitochondrial dysfunction and decreased availability of adenosine triphosphate (ATP).


Iron Homeostasis Sideroblastic Anemia Hypoxic Hypoxia Hepcidin mRNA Hepcidin Production 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science + Business Media Inc. 2008

Authors and Affiliations

  • S. Brandt
    • 1
  • J. Takala
    • 2
  • P. M. Lepper
    • 2
  1. 1.Department of AnesthesiologyUniversity Hospital InselspitalBernSwitzerland
  2. 2.Department of Intensive CareUniversity Hospital InselspitalBernSwitzerland

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