Blood Purification Techniques in Sepsis and SIRS

  • P. M. Honoré
  • O. Joannes-Boyau
  • B. Gressens
Conference paper


The rationale for blood purification in sepsis has been a matter of debate for 25 years. For more than a decade [1], it has been suggested that a reduction in cytokines and other mediators in the blood compartment could, in theory, lead to a reduction in mortality in patients with sepsis and the systemic inflammatory response syndrome (SIRS). However, as the pharmacodynamics and pharmacokinetics of cytokines are complex, it seems likely that this is an oversimplification.


Renal Replacement Therapy Systemic Inflammatory Response Syndrome Continuous Renal Replacement Therapy Blood Compartment Blood Purification 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science + Business Media Inc. 2008

Authors and Affiliations

  • P. M. Honoré
    • 1
  • O. Joannes-Boyau
    • 2
  • B. Gressens
    • 1
  1. 1.Department of Intensive CareSt-Pierre Para-Universitary HospitalOttignies-Louvain-La-NeuveBelgium
  2. 2.Department of Intensive Care Haut Leveque University HospitalUniversity of Bordeaux IIPessacFrance

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