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Protective Mechanical Ventilation: Lessons Learned From Alveolar Mechanics

  • S. Albert
  • B. Kubiak
  • G. Nieman

Abstract

Acute respiratory distress syndrome (ARDS) is a serious pulmonary disease characterized by respiratory failure with marked hypoxemia secondary to diffuse bilateral non-hydrostatic pulmonary edema and atelectasis. A formal definition of ARDS and acute lung injury (ALI) was introduced by an American-European Consensus Conference [1]. ALI has a devastating clinical impact, and current data estimates 190,600 new cases of ALI per year with 74,500 annual deaths in the United States alone [2]. The majority of patients with ALI, and in particular ARDS, require supportive therapy with mechanical ventilation. It has been shown, both clinically and experimentally, that improper mechanical ventilation causes ventilator-induced lung injury (VILI), which exacerbates the underlying ALI, leading to an increase in mortality [3].

Keywords

Acute Lung Injury Acute Respiratory Distress Syndrome Electrical Impedance Tomography Acute Respiratory Distress Syndrome Patient Airway Pressure Release Ventilation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science + Business Media Inc. 2008

Authors and Affiliations

  • S. Albert
    • 1
  • B. Kubiak
    • 1
  • G. Nieman
    • 1
  1. 1.Department of SurgerySuny Upstate Medical UniversitySyracuseUSA

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