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Genetic Susceptibility in ALI/ARDS: What have we Learned?

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Intensive Care Medicine

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Abstract

Since its initial description in 1967 [1], and subsequent definition in 1992 by the American-European Consensus Conference [2], acute lung injury/acute respiratory distress syndrome (ALI/ARDS) and all the different facets of this devastating illness — etiology, pathophysiology, epidemiology, management, and genetics — have become better understood. Recent reports from the United States document that this syndrome affects 190,000 patients annually with a mortality exceeding 35% [3]. The incidence in European countries and Australia varies significantly, but is generally lower, ranging from 16 to 34 cases per 100,000 person-years at risk [4–6].

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Author information

Authors and Affiliations

  1. Department of Internal Medicine Division of Pulmonary, Critical Care Medicine Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA

    R. Cartin-Ceba & O. Gajic

  2. Department of Pulmonary, Critical Care, Sleep Medicine Department of Medicine Mount Sinai Hospital, 1190 Fifth Avenue, New York, NY, 10029, USA

    M. N. Gong

Authors
  1. R. Cartin-Ceba
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  2. M. N. Gong
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  3. O. Gajic
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Editor information

Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Université libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium

    Jean-Louis Vincent MD, PhD, FCCM, FCCP (Head) (Head)

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Cartin-Ceba, R., Gong, M.N., Gajic, O. (2008). Genetic Susceptibility in ALI/ARDS: What have we Learned?. In: Vincent, JL. (eds) Intensive Care Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-77383-4_2

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  • DOI: https://doi.org/10.1007/978-0-387-77383-4_2

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-77382-7

  • Online ISBN: 978-0-387-77383-4

  • eBook Packages: MedicineMedicine (R0)

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