Genetic Susceptibility in ALI/ARDS: What have we Learned?

  • R. Cartin-Ceba
  • M. N. Gong
  • O. Gajic
Conference paper


Since its initial description in 1967 [1], and subsequent definition in 1992 by the American-European Consensus Conference [2], acute lung injury/acute respiratory distress syndrome (ALI/ARDS) and all the different facets of this devastating illness — etiology, pathophysiology, epidemiology, management, and genetics — have become better understood. Recent reports from the United States document that this syndrome affects 190,000 patients annually with a mortality exceeding 35% [3]. The incidence in European countries and Australia varies significantly, but is generally lower, ranging from 16 to 34 cases per 100,000 person-years at risk [4, 5, 6].


Acute Lung Injury Acute Respiratory Distress Syndrome Respir Crit Adult Respiratory Distress Syndrome Genetic Epidemiology 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science + Business Media Inc. 2008

Authors and Affiliations

  • R. Cartin-Ceba
    • 1
  • M. N. Gong
    • 2
  • O. Gajic
    • 1
  1. 1.Department of Internal Medicine Division of PulmonaryCritical Care Medicine Mayo ClinicRochesterUSA
  2. 2.Department of Pulmonary, Critical CareSleep Medicine Department of Medicine Mount Sinai HospitalNew YorkUSA

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