Mouse Models of Adrenal Tumorigenesis

  • Felix Beuschlein


Over the past decade, a number of high-throughput techniques have emerged as powerful tools for molecular and functional characterization of cancer cells. These techniques allow for genetic or epigenetic analysis of DNA, determination of RNA expression pattern, proteomic profiling, or characterization of posttranslational modification. Despite these technical advances that aid thorough molecular characterization of surgical tumor material, most of the functional properties of biological molecules are still unpredictable from pure expression and sequence analysis. For functional studies of gene products, mouse models continue to be intensively utilized as an experimental system due to the similarity to humans with respect to genome organization, development, and physiology.


Adrenal Cortex Adrenal Tumor Gastric Inhibitory Polypeptide Inbred Mouse Strain Adrenocortical Tumor 
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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Department of MedicineEndocrine Research, University Hospital InnenstadtMunichGermany

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