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Beckwith–Wiedemann Syndrome

  • Michael DeBaun
  • Jennifer Horst
Chapter

Abstract

Beckwith-Wiedemann syndrome (BWS) (OMIM 130650) is a disease of prenatal overgrowth, congenital malformations, and predisposition to cancer. The syndrome was independently described by J.B. Beckwith, an American pathologist, at the annual meeting of the Western Society for Pediatric Research in 1963 [1] and H.R. Wiedemann, a German pediatrician, in 1964 [2]. This disease was initially referred to as the EMG syndrome for its most prominent clinical features that distinguished the syndrome from other congenital malformations: exomphalos, macroglossia, and gigantism.

Keywords

Cancer Screening Adrenocortical Carcinoma Neonatal Hypoglycemia Abnormal Methylation Adrenal Hypoplasia Congenita 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Division of Pediatric Hematology-Oncology, Department of PediatricsWashington University School of MedicineSt. LouisUSA
  2. 2.Department of PediatricsWashington University School of Medicine, Washington UniversitySt. LouisUSA

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