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The Role of Reelin in Etiology and Treatment of Psychiatric Disorders

  • S. Hossein Fatemi
  • Teri J. Reutiman
  • Timothy D. Folsom

There are many brain proteins that participate in the early growth and development of the mammalian central nervous system. Reelin is a glycoprotein that helps guide brain development in an orderly fashion. Changes in the level of this protein or its receptors or downstream proteins may cause abnormal corticogenesis and alter synaptic plasticity. These changes have also been observed in a number of neuropsychiatric disorders. We will discuss more about this protein and its possible involvement in various neuropsychiatric disorders.

Keywords

Bipolar Disorder Reeler Mouse ApoE Receptor Reelin Signaling Reelin Expression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 2008

Authors and Affiliations

  • S. Hossein Fatemi
    • 1
  • Teri J. Reutiman
    • 2
  • Timothy D. Folsom
    • 2
  1. 1.Departments of Psychiatry, Pharmacology, and NeuroscienceUniversity of Minnesota Medical SchoolMinneapolis55455
  2. 2.Department of PsychiatryUniversity of Minnesota Medical SchoolMinneapolis55455

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