Genetic Analysis of Conduct Disorder and Antisocial Behavior

  • Soo Hyun Rhee
  • Irwin D. Waldman

In this chapter, we examine the evidence for genetic influences on conduct disorder and antisocial behavior. First, we present results from a meta-analysis of twin and adoption studies estimating the relative magnitude of genetic and environmental influences on antisocial behavior (Rhee & Waldman, 2002). Second, we discuss recent studies that have examined several interesting issues in the etiology of antisocial behavior, including genotype × environment interactions, co-occurrence with other psychiatric disorders, the etiology of psychopathy, and the etiology of adolescent-limited versus life-course-persistent antisocial behavior. Third, we review association studies examining the influence of specific candidate genes on antisocial behavior and linkage studies conducting genome-wide screens for quantitative trait loci (QTLs) influencing antisocial behavior.


Antisocial Behavior Twin Study Conduct Disorder A218C Polymorphism Adoption Study 
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© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Institute for Behavioral GeneticsUniversity of ColoradoBoulderUSA
  2. 2.Department of PsychologyEmory UniversityAtlantaUSA

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