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Magnetic Nanoparticle Assisted Molecular MR Imaging

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Bio-Applications of Nanoparticles

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 620))

Abstract

Magnetic nanoparticles exhibit unique nanoscale properties of superparamagnetism and have the potential to be utilized as excellent probes for magnetic resonance imaging (MRI). Especially, clinically benign iron oxide nanoparticles provide good MR probing capability and some of them are currently available for clinical applications. However, limited magnetic property and inability to escape from reticuloendothelial system (RES) of the currently used nanoparticles impede their further advancements and therefore it is necessary to develop advanced magnetic nanoparticle probes for next-generation molecular MR imaging. In this chapter, we overview recent progresses on the development of magnetic nanoparticle probes for molecular MR imaging. Utilization of these nanoparticle probes for both in vitro and in vivo molecular MR imaging will be described.

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Author information

Authors and Affiliations

  1. Department of Chemistry, Yonsei University, Seoul, 120-749, Korea

    Young-wook Jun, Jung-tak Jang & Jinwoo Cheon

  2. Nano-Medical National Core Research Center, Yonsei University, Seoul, 120-749, Korea

    Young-wook Jun, Jung-tak Jang & Jinwoo Cheon

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  1. Young-wook Jun
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  2. Jung-tak Jang
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  3. Jinwoo Cheon
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Editors and Affiliations

  1. Institute of Biomaterials and Biomedical Engineering, The Terrence Donnelly, Centre for Cellular and Biomolecular Research, Materials Science and Engineering, Toronto, Ontario, Canada

    Warren C. W. Chan Ph.D.

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Jun, Yw., Jang, Jt., Cheon, J. (2007). Magnetic Nanoparticle Assisted Molecular MR Imaging. In: Chan, W.C.W. (eds) Bio-Applications of Nanoparticles. Advances in Experimental Medicine and Biology, vol 620. Springer, New York, NY. https://doi.org/10.1007/978-0-387-76713-0_7

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