Descemet’s Stripping Endothelial Keratoplasty (DSEK) and Glaucoma

  • Theodoros Filippopoulos
  • Kathryn A. Colby
  • Cynthia L. Grosskreutz


Posterior lamellar corneal procedures are gaining widespread acceptance as the surgical procedure of choice in cases of endo­thelial dysfunction. These offer more rapid visual recovery and more predictable refractive outcomes compared to penetrating keratoplasty. Originally developed by Melles and modified by Terry, deep lamellar endothelial keratoplasty (DLEK) evolved into Descemet stripping endothelial keratoplasty with (DSAEK) or without (DSEK) the use of an automated microkeratome. As the procedure and the pertinent instrumentation are undergoing refinements, little is known about the management of glaucoma that may coexist or arise as a result of posterior lamellar corneal procedures. We will review the available information on the incidence of glaucoma after DSEK/DLEK, the error of measurement in intraocular pressure (IOP) with the Goldmann applanation tonometer (GAT) and summarize considerations about the surgical management of glaucoma in patients after DSEK/DLEK.


Central Corneal Thickness Glaucoma Medication Endothelial Cell Loss Bullous Keratopathy Glaucoma Drainage Device 
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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Theodoros Filippopoulos
    • 1
    • 2
  • Kathryn A. Colby
    • 3
  • Cynthia L. Grosskreutz
    • 4
  1. 1.Department of OphthalmologyMassachusetts Eye & Ear Infirmary, Harvard Medical SchoolBostonUSA
  2. 2.Athens Vision Eye InstituteKallitheaGreece
  3. 3.Department of Ophthalmology, Cornea ServiceMassachusetts Eye and Ear Infirmary, Harvard Medical SchoolBostonUSA
  4. 4.Glaucoma Service, Department of OphthalmologyMassachusetts Eye & Ear Infirmary, Harvard Medical SchoolBostonUSA

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