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Monocular Drug Trials for Glaucoma Therapy in the Community Setting

  • Tony Realini
Chapter

Abstract

The clinical management of glaucoma would be far simpler if all patients responded equally well to therapy with IOP-lowering medication. Unfortunately, this is not the case. Consider that timolol offers median IOP reduction of approximately 5-6 mmHg. This does not mean that every patient will manifest a 5-6 mmHg IOP reduction. Rather, it means that half of the patients will enjoy an IOP reduction exceeding this median amount, while the other half will have a lesser IOP reduction. There is currently no way of identifying a priori how patients will respond to their medication; we are limited to a trial and error approach, a so-called n-of-one trial.

Keywords

Glaucoma Patient Topical Carbonic Anhydrase Inhibitor Bilateral Therapy Monocular Trial Latanoprost Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Tony Realini
    • 1
  1. 1.Department of OphthalmologyWest Virginia UniversityMorgantownUSA

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