Inflammatory Disease and Glaucoma
Elevated intraocular pressure (IOP) is a common, but challenging complication of ocular inflammation. When IOP elevation in the setting of uveitis is temporary and does not damage the optic nerve, the term uveitis-related ocular hypertension is most appropriate. Uveitic “glaucoma” must be reserved for cases of uveitis in which elevated IOP is associated with optic nerve damage, which manifests as changes in the optic nerve structure and/or the presence of visual field defects. The overall prevalence of secondary glaucoma in all forms of uveitis has been reported to be between 5 and 19% in adults and from 5 to 13.5% in children. Anterior uveitis, older age at presentation, and chronic inflammation are all related to a higher prevalence of uveitic glaucoma. Certain types of uveitis, such as herpetic keratouveitis and anterior uveitis, associated with Juvenile Idiopathic Arthritis are also associated with a higher prevalence of secondary glaucoma.
KeywordsOcular Hypertension Trabecular Meshwork Anterior Uveitis Angle Closure Primary Open Angle Glaucoma
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