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Cystic and Mucinous Lesions: Mucocele and Low-Grade Mucoepidermoid Carcinoma

  • William C. Faquin
  • Celeste N. Powers
Part of the Essentials in Cytopathology Series book series (EICP, volume 5)

Cystic lesions are estimated to account for up to 8% of all salivary gland masses. They represent a wide range of salivary gland pathology from the non-neoplastic mucocele, salivary duct cyst, and sclerosing polycystic adenosis, to benign tumors such as cystadenoma and Warthin tumor, to malignant cystic tumors, including low-grade mucoepidermoid carcinoma and cystadenocarcinoma. In some cases, cystic degeneration occurs in what are ordinarily noncystic tumors such as pleomorphic adenoma and basal cell adenoma, and some tumors have cystic variants such as the papillary cystic subtype of acinic cell carcinoma. In the parotid gland, cystic lesions also include the difficult differential diagnosis of lymphoepithelial cysts, and metastatic cystic squamous cell carcinoma to an intraparotid lymph node. Of all of these entities, the most commonly encountered differential diagnostic problem is the cytologic distinction between mucocele and low-grade mucoepidermoid carcinoma. This chapter will focus foremost upon this common diagnostic problem, followed by an examination of other differential diagnostic entities.

Keywords

Salivary Gland Pleomorphic Adenoma Salivary Gland Tumor Mucoepidermoid Carcinoma Acinic Cell Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Brandwein MS, Ivanov K, Wallace DI, et al. Mucoepidermoid carcinoma: a clinicopathologic study of 80 patients with special reference to histological grading. Am J Surg Pathol 2001;25:835–845.PubMedCrossRefGoogle Scholar
  2. Cheuk W, Chan JKC. Advances in salivary gland pathology. Histopathology 2007;51:1–20.PubMedCrossRefGoogle Scholar
  3. Droese M. Cytological diagnosis of sialadenosis, sialadenitis, and parotid cysts by fine-needle aspiration biopsy. Adv Oto-Rhino-Layng 1981;26:49–96.Google Scholar
  4. Edit D, Pilch BZ, Osgood R, Faquin WC. Fine-needle aspiration biopsy in sclerosing polycystic adenosis. Diagn Cytopathol 2007;35–444–447.CrossRefGoogle Scholar
  5. Goode RK, Auclair PL, Ellis GL. Mucoepidermoid carcinoma of the major salivary glands: clinical and histopathologic analysis of 234 cases with evaluation of grading criteria. Cancer 1998;82:1217.PubMedCrossRefGoogle Scholar
  6. Jahan-Parwar B, Huberman RM, Donovan DT, Schwartz MR, Ostrowski ML. Oncocytic mucoepidermoid carcinoma of the salivary glands. Am J Surg Pathol 1999;23:523–529.PubMedCrossRefGoogle Scholar
  7. Klijanienko J, Vielh P. Fine-needle sampling of salivary gland lesions. IV. Review of 50 cases of mucoepidermoid carcinoma with histologic correlation. Diagn Cytopathol 1997;17:92–98PubMedCrossRefGoogle Scholar
  8. Layfield LJ, Gopez EV. Cystic lesions of the salivary glands: cytologic features in fine-needle aspiration biopsies. Diagn Cytopathol 2002;27:197–204.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • William C. Faquin
    • 1
  • Celeste N. Powers
    • 2
  1. 1.Department of Pathology, Massachusetts General HospitalHarvard Medical SchoolBostonUSA
  2. 2.Department of Pathology, Medical College of Virginia HospitalsVirginia Commonwealth UniversityRichmondUSA

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