Spindle Cell Tumors: Spindled Myoepithelioma, Myoepithelial-Predominant Pleomorphic Adenoma, and Schwannoma

  • William C. Faquin
  • Celeste N. Powers
Part of the Essentials in Cytopathology Series book series (EICP, volume 5)

As in other anatomic sites, FNA of spindle cell lesions of the salivary glands is a very challenging area of cytopathology. This is due in part to the wide range of benign and malignant neoplastic tumors as well as reactive lesions with a spindle cell cytomorphology that may be encountered. In addition to the variety of lesions, salivary gland tumors with a predominant spindle cell pattern are rare, accounting for less than 3% of salivary gland aspirates. The most common spindle cell lesions of the salivary gland are myoepithelial-predominant pleomorphic adenoma, myoepithelioma, and schwannoma, which will be the focus of this chapter. Other rare, but important, spindle cell lesions in the differential diagnosis, including nodular fasciitis, solitary fibrous tumor, myoepithelial carcinoma, spindle cell carcinoma, and melanoma, will also be discussed.


Salivary Gland Spindle Cell Parotid Gland Synovial Sarcoma Pleomorphic Adenoma 
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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • William C. Faquin
    • 1
  • Celeste N. Powers
    • 2
  1. 1.Department of Pathology, Massachusetts General HospitalHarvard Medical SchoolBostonUSA
  2. 2.Department of Pathology, Medical College of Virginia HospitalsVirginia Commonwealth UniversityRichmondUSA

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