Pap Smear



The Pap smear for cervical cancer screening was first introduced in the 1940s. Since then, the incidence of cervical cancer in the US has decreased from 14/100,000 to 7.8/100,000 in 1994 [1]. Despite this decline, cervical cancer continues to be the third most common gynecologic malignancy in the US and the second most common cancer in women worldwide. This underscores the need for continued vigilance.


Cervical Cancer Human Papilloma Virus Endometrial Biopsy Atypical Squamous Cell Dorsal Lithotomy Position 


  1. 1.
    United States Preventive Services Task Force. Screening for cervical cancer.Google Scholar
  2. 2.
    Amer College of Obstetricians and Gynecologists. Cervical cytology screening. Practice Bulletin 45. Washington, DC:ACOG, 2003.Google Scholar
  3. 3.
    Bernstein SJ, Sanchez-Ramos L, Ndubisi B. Liquid-based cervical cytologic smear study and conventional Papsnicolaou smears: a metaanalysis of prospective studies comparing cytologic diagnosis and sample adequacy. Am J Obstet Gynecol 2001;185:308–317.PubMedCrossRefGoogle Scholar
  4. 4.
    Nance KV. Evolution of pap testing at a community hospital – a ten year experience. Diagn Cytopathol 2007;35:148–153.PubMedCrossRefGoogle Scholar
  5. 5.
    Sweeny BJ, Haq Z, Happel JF, Weinstein B, Schneider D. Comparison of the effectiveness of two liquid based papanicoleau systems in the handling of adverse limiting factors, such as excessive blood. Cancer 2006;108(1):27–31.CrossRefGoogle Scholar
  6. 6.
    Twu NF, Chen YJ, Want PH, Yu BKJ, Lai CR, Chao KC, Yuan CC, Yen MS. Improved cervical cancer screening in premenopausal women by combination of Pap smear and speculoscopy. Eur J Obstet Gynecol Reprod Biol 2007;133(1):114–118.PubMedCrossRefGoogle Scholar
  7. 7.
    Loiudice I, Abbiati R, Boselli F, Cecchini G, Costa S, Grossi E, Piccoli R, Villani C. Improvement of Pap smear sensitivity using a visual adjunctive procedure: a cooperative Italian study on speculoscopy (GISPE). Eur J Cancer Prev 1998;7(4):295–304.PubMedCrossRefGoogle Scholar
  8. 8.
    Wright TC, Massad L, Dunton C, Spitzer M, Wilkinson E, Solomon D. 2006 Consensus guidelines for the management of women with abnormal cerical cancer screening tests. Am J Obstet Gynecol 2007;197(4):346–355.PubMedCrossRefGoogle Scholar
  9. 9.
    Amer College of Obstetricians and Gynecologists. Cervical Cytology Screening. Practice Bulletin 109. Washington, DC: ACOG, December 2009.Google Scholar
  10. 10.
    Wright TC, Cox JT, Massad LS. 2001 Consensus guidelines for the management of women with cervical cytological abnormalities. JAMA 2002;287:2120–2129.PubMedCrossRefGoogle Scholar

Additional Resources Articles

  1. Solomon D, Davey D, Kurman R. The 2001 Bethesda System terminology for reporting results of cervical cytology. JAMA 2002;287:2114–2119.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Family MedicineSt. Joseph’s Hospital Health CenterFayettevilleUSA

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