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Cervical Cryotherapy

  • Laurie Turenne-Kolpan
Chapter

Abstract

Cryotherapy is an ablative technique that has been used to treat all grades of cervical dysplasia for more than 50 years. It is a preferred method of many primary care providers because of its cost-effectiveness, safety, and ease in performance. Cryotherapy causes destruction of cells by producing a rapid freezing of tissue followed by a slow thaw. This causes intracellular ice crystals to form, followed by expansion of intracellular material, leading to rupture of the cells [1]. The depth of freezing is directly proportional to the length of ice ball formation around the side of the probe, so that an ice ball 7-mm thick around the probe will yield a depth of freezing equal to 7 mm [2]. It is important to note that the temperature of the tissue in the distal 2 mm of the ice ball is insufficient to cause cell death, so the level of actual tissue destruction is generally 2 mm less than the thickness of the ice ball [1].

Keywords

Cervical Intraepithelial Neoplasia Cervical Dysplasia Moderate Dysplasia Squamocolumnar Junction External Genital Wart 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Family PracticeHunterdon Medical CenterFlemingtonUSA

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