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Multifunctional Nanotherapeutics for Cancer

  • T. Minko
  • J. J. Khandare
  • A. A. Vetcher
  • V. A. Soldatenkov
  • O. B. Garbuzenko
  • M. Saad
  • V. P. Pozharov
Part of the Fundamental Biomedical Technologies book series (FBMT, volume 4)

Nanotechnology, as a field of applied science, focuses on the development, production, characterization and application of materials, and devices at the level of molecules and atoms with a typical size between 10−9 nm and 10−6 μm. Nanotherapeutics, a rapidly expanding area of medicine, uses nanotechnology products for highly specific medical interventions at the molecular scale for curing diseases or repairing damaged tissues. Although some nanotechnology products can be applied alone as therapeutic or imaging agents, they are being most often used as pharmaceutical nanocarriers for delivering drugs or imaging agents to the site of the action in desired quantities and releasing therapeutic loads with a specific time profile. Linear and branched polymers, dendrimers, quantum dots, nanoparticles, nanospheres, nanotubes, nanocrystals, nanogels, liposomes, micelles, as well as other types of nanocarriers are being employed in different fields of medicine for diagnostics, imaging, treatment, and prophylaxis of many pathological conditions (Fig. 1)

Keywords

Anticancer Drug Malignant Pleural Mesothelioma PAMAM Dendrimer Brain Tumor Cell Drug Efflux Pump 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • T. Minko
    • 1
  • J. J. Khandare
    • 1
  • A. A. Vetcher
    • 2
  • V. A. Soldatenkov
    • 3
  • O. B. Garbuzenko
    • 1
  • M. Saad
    • 1
  • V. P. Pozharov
    • 1
  1. 1.Department of PharmaceuticsThe State University of New JerseyPiscatawayUSA
  2. 2.National Center for Biodefense and Infectious DiseasesGeorge Mason UniversityManassasUSA
  3. 3.Department of Radiation MedicineGeorgetown University Medical CenterWashingtonUSA

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