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Clinical Evaluation of Dementia and When to Perform PET

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PET in the Evaluation of Alzheimer's Disease and Related Disorders
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The number and proportion of adults over 65 years is expected to increase rapidly over the next several decades. According to projections from the United States Bureau of the Census, 1 between the years 2000 and 2030, the population aged 65 and over is expected to double from 35 to over 70 million. The largest proportion of older adults will be between the ages of 65 and 74 years, and the largest growth is projected to occur in individuals 85 years and older, increasing from 4.3 to 8.8 million. Because age is the greatest risk factor for dementia, as the population of elderly people increases, so will the number of patients suffering from dementia. Given that early treatment interventions are able to keep patients at higher levels of functioning and future innovative therapies may be able to delay the onset of dementia and slow its progression, it is becoming increasingly important to accurately diagnose dementia as early as possible. This chapter outlines the basic elements of a clinical diagnostic evaluation for Alzheimer’s disease (AD) and other dementias; and also addresses how to identify candidates for a dementia evaluation, discusses the role of neuroimaging in a clinical dementia evaluation, and identifies future directions

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Ercoli, L.M., Small, G.W. (2009). Clinical Evaluation of Dementia and When to Perform PET. In: Silverman, D. (eds) PET in the Evaluation of Alzheimer's Disease and Related Disorders. Springer, New York, NY. https://doi.org/10.1007/978-0-387-76420-7_1

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