Baboons and other nonhuman primates have come to play an increasingly important role over the past 30 years as experimental subjects in the area of drug abuse research due to their extensive physiological, anatomical, and behavioral similarities to humans. Compared with other Old World monkeys, the relatively large size of baboons originally made them ideal subjects for drug self-administration and chronic intragastric drug administration studies requiring indwelling catheters. Such studies resulted in the seminal finding of a high concordance between those psychoactive drugs that are self-administered by baboons and those that are abused by humans (Brady et al., 1987, 1990).
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Hienz, R.D., Weerts, E.M. (2009). Baboons in Drug Abuse Research. In: VandeBerg, J.L., Williams-Blangero, S., Tardif, S.D. (eds) The Baboon in Biomedical Research. Developments in Primatology: Progress and Prospects. Springer, New York, NY. https://doi.org/10.1007/978-0-387-75991-3_16
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